Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.67 |
| ▸ | PPARA | Q07869 | 12/20 | 0.64 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283066 | 0.97 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL6283013 | 0.97 | PPARG (0.68) | PPARGPPARAPPARD | |
| Hydrochloric Acid SCHEMBL6283435 | 0.96 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL6285657 | 0.93 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL6674254 | 0.93 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL6674246 | 0.93 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL6283473 | 0.93 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL6674251 | 0.92 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL6284844 | 0.91 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL6286930 | 0.91 | PPARG (0.60) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933309-B2 | Halogenobenzyl aminopropionic acid derivatives | TOAEIYO LTD. (JP) | 2005-08-23 | — | — | US | disclosed |
| US-20040102439-A1 | Halogenobenzyl aminopropionic acid derivatives | TOAEIYO LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102439-A1 | Halogenobenzyl aminopropionic acid derivatives | FABP4, SLC5A1, ALDH7A1 | PPARG 34/4885PPARA 24/4885PPARD 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.