Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SI | P14410 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283755 | 0.86 | MAPT (0.51) | MEN1KMT2AALDH1A1TP53ABL1 | |
| SCHEMBL8425157 | 0.79 | ESR1 (0.44) | MEN1KMT2ACYP3A4CYP2C9ABL1 | |
| SCHEMBL6286685 | 0.76 | MAPT (0.45) | MEN1KMT2AALDH1A1KDM4ETP53 | |
| SCHEMBL18593394 | 0.75 | ABL1 (0.59) | HSP90AA1MEN1KMT2ATP53ABL1 | |
| SCHEMBL29810161 | 0.75 | ABL1 (0.59) | HSP90AA1MEN1KMT2ATP53ABL1 | |
| SCHEMBL5370456 | 0.72 | ERN1 (0.56) | HSP90AA1MEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL5273487 | 0.72 | PRF1 (0.42) | MEN1KMT2AALDH1A1CYP3A4KDM4E | |
| SCHEMBL28092583 | 0.70 | MGAM (0.54) | HSP90AA1KDM4ETP53HSD17B10ABL1 | |
| SCHEMBL7504214 | 0.70 | ERN1 (0.55) | HSP90AA1MEN1KMT2ACYP2C19ABL1 | |
| SCHEMBL5542674 | 0.70 | CA2 (0.38) | MEN1KMT2AALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921827-B2 | Process for preparing 3-aryl-benzo{b} thiophenes | ELI LILLY AND COMPANY (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040132775-A1 | Process for preparing 3-aryl-benzo{b} thiophenes | LUKE WAYNE DOUGLAS (US) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132775-A1 | Process for preparing 3-aryl-benzo{b} thiophenes | TBCB, CYP1B1, TST | HSP90AA1 1600/4885MEN1 1793/4885KMT2A 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.