Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283572 | 0.86 | HSP90AA1 (0.49) | MAPTALDH1A1SMN1; SMN2GPR55LMNA | |
| SCHEMBL6286685 | 0.83 | MAPT (0.45) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5368387 | 0.79 | MAOB (0.54) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7501599 | 0.78 | MAOB (0.53) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1704521 | 0.74 | ABL1 (0.62) | MAPTALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL5273487 | 0.73 | PRF1 (0.42) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5542674 | 0.71 | CA2 (0.38) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL22072873 | 0.69 | ABL1 (0.52) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL27755757 | 0.69 | SYK (0.56) | MAPTALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL12715050 | 0.69 | ABL1 (0.79) | MAPTSMN1; SMN2LMNATP53ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921827-B2 | Process for preparing 3-aryl-benzo{b} thiophenes | ELI LILLY AND COMPANY (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040132775-A1 | Process for preparing 3-aryl-benzo{b} thiophenes | LUKE WAYNE DOUGLAS (US) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132775-A1 | Process for preparing 3-aryl-benzo{b} thiophenes | TBCB, CYP1B1, TST | MAPT 2868/4885ALDH1A1 2025/4885SMN1; SMN2 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.