Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433668 | 0.79 | KDR (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL30824770 | 0.77 | CHEK1 (0.44) | — | |
| SCHEMBL211026 | 0.77 | L3MBTL1 (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| Ammonia Solution, Strong SCHEMBL27959164 | 0.75 | L3MBTL1 (0.54) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL10480215 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDERN1HSD17B10 | |
| SCHEMBL10480168 | 0.75 | STK10 (0.42) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL2262245 | 0.74 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL11323197 | 0.73 | PRMT1 (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL11327793 | 0.72 | L3MBTL1 (0.49) | KDM4EMAPT | |
| SCHEMBL642228 | 0.72 | HDAC4 (0.58) | HDAC4HDAC2HDAC8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958395-B2 | Method for producing water-soluble saccharide conjugates and saccharide mimetics by Diels-Alder reaction | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2005-10-25 | — | — | US | disclosed |
| US-20040059101-A1 | Method for producing water-soluble saccharide conjugates and saccharide mimetics by diels-alder reaction | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2004-03-25 | — | — | US | disclosed |
| EP-1313750-A1 | METHOD FOR PRODUCING WATER-SOLUBLE SACCHARIDE CONJUGATES AND SACCHARIDE MIMETICS BY DIELS-ALDER REACTION | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016378-A1 | METHOD FOR PRODUCING WATER-SOLUBLE SACCHARIDE CONJUGATES AND SACCHARIDE MIMETICS BY DIELS-ALDER REACTION | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059101-A1 | Method for producing water-soluble saccharide conjugates and saccharide mimetics by diels-alder reaction | SI, MAN1B1, SORD | HDAC4 2276/4885HDAC2 2604/4885HDAC8 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.