Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PARK7 | Q99497 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503347 | 0.92 | MAOB (0.56) | MAOBBCHEACHECES1CDC25A | |
| SCHEMBL9050379 | 0.91 | MAOB (0.55) | MAOBBCHEACHEALDH1A1ALDH2 | |
| SCHEMBL6284752 | 0.83 | CES1 (0.40) | MAOBBCHEACHEALDH1A1ALDH2 | |
| SCHEMBL6280419 | 0.77 | CES1 (0.42) | BCHEALDH1A1ALDH2ALDH3A1CES1 | |
| SCHEMBL27452434 | 0.77 | ALDH1A1 (0.51) | ALDH1A1ALDH2ALDH3A1PKMPARK7 | |
| SCHEMBL9054162 | 0.76 | MAOB (0.57) | MAOBBCHEACHECES1CDC25A | |
| SCHEMBL4500323 | 0.76 | MAOB (0.51) | MAOBBCHEACHE | |
| SCHEMBL9047059 | 0.75 | MAOB (0.50) | MAOBBCHEACHE | |
| SCHEMBL9062737 | 0.73 | MAOB (0.64) | MAOBBCHEACHECES1CDC25A | |
| SCHEMBL9096146 | 0.73 | DRD2 (0.55) | ALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906090-B1 | Compositions and methods for treating mycobacterial diseases | ASTRAZENECA AB (SE) | 2005-06-14 | — | — | US | disclosed |