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SCHEMBL9054162

SCHEMBL9054162

CCN(CCCCCN1C(=O)C(=O)c2cc(N3CCCCC3)ccc21)Cc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 6/20 0.57
▸ BCHE P06276 2/20 0.57
▸ ACHE P22303 2/20 0.57
▸ CES1 P23141 1/20 0.42
▸ CDC25A P30304 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4503347 0.83 MAOB (0.56) MAOBBCHEACHECES1CDC25A
SCHEMBL9062737 0.82 MAOB (0.64) MAOBBCHEACHECES1CDC25A
SCHEMBL9053947 0.82 MAOB (0.76) MAOBBCHEACHECES1CDC25A
SCHEMBL9050379 0.81 MAOB (0.55) MAOBBCHEACHE
SCHEMBL9053218 0.81 MAOB (0.63) MAOBBCHEACHE
SCHEMBL9051412 0.81 PARK7 (0.63) MAOBBCHEACHE
SCHEMBL6280891 0.81 MAOB (0.75) MAOBBCHEACHECES1CDC25A
SCHEMBL6284754 0.76 MAOB (0.45) MAOBBCHEACHECES1CDC25A
SCHEMBL6282796 0.74 DRD2 (0.57) BCHEACHE
SCHEMBL9149764 0.72 BCHE (0.55) MAOBBCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0703901-A1 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE Astra Aktiebolag (SE) 1996-04-03 — — EP disclosed
WO-1994029272-A1 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE ASTRA AKTIEBOLAG (SE) 1994-12-22 — — WO disclosed