Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284804 | 0.90 | CA2 (0.49) | CA2ALDH1A1KMT2AADORA1KDM4E | |
| SCHEMBL1850788 | 0.84 | CA2 (0.53) | CA2ALDH1A1KMT2AADORA1KDM4E | |
| Anthranilamide SCHEMBL6288989 | 0.83 | STING1 (0.49) | ALDH1A1HSD17B10CFTRBCL2L1 | |
| SCHEMBL17858541 | 0.79 | BCL2L1 (0.50) | ALDH1A1KDM4EBCL2L1NPC1RAB9A | |
| Anthranilamide SCHEMBL6280290 | 0.78 | KMT2A (0.67) | CA2ALDH1A1KMT2AADORA2AADORA2B | |
| SCHEMBL15697569 | 0.77 | BCL2L1 (0.46) | CA2ALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL3252698 | 0.76 | BCL2L1 (0.53) | CA2ALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL3254246 | 0.75 | GAA (0.57) | ALDH1A1KMT2AHPGDHSD17B10NPC1 | |
| SCHEMBL2895989 | 0.75 | ALDH1A1 (0.55) | CA2ALDH1A1KMT2AADORA1KDM4E | |
| SCHEMBL6284802 | 0.75 | LMNA (0.51) | CA2ALDH1A1ADORA1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005508311-A | — | — | 2005-03-31 | — | — | JP | claimed |
| EP-1416928-A2 | N-MONOACYLATED DERIVATIVES OF O-PHENYLENEDIAMINES, THEIR SIX MEMBERED HETEROCYCLIC ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | claimed |
| WO-2003013484-A2 | N-MONOACYLATED DERIVATIVES OF O-PHENYLENEDIAMINES, THEIR SIX MEMBERED HETEROCYCLIC ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-02-20 | — | — | WO | claimed |