Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 12/20 | 0.72 |
| ▸ | TOP2A | P11388 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239227 | 0.90 | MAOA (0.74) | MAOATOP2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL8484364 | 0.84 | MAOA (1.00) | MAOATOP2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL14466272 | 0.83 | MAOA (0.74) | MAOATOP2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL5346660 | 0.82 | MAOA (0.72) | MAOATOP2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL14443986 | 0.81 | MAOA (0.71) | MAOATOP2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL5350979 | 0.79 | MAOA (0.74) | MAOATOP2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL11031301 | 0.77 | MAOA (0.64) | MAOATOP2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL14443985 | 0.76 | MAOA (0.74) | MAOATOP2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL5354713 | 0.76 | MAOA (0.72) | MAOATOP2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL14443982 | 0.75 | MAOA (0.71) | MAOATOP2AKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933396-B2 | Process to prepare psorospermin | CYLENE PHARMACEUTICALS (US) | 2005-08-23 | — | — | US | disclosed |
| US-20040102515-A1 | Process to prepare psorospermin | CYLENE PHARMACEUTICALS | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102515-A1 | Process to prepare psorospermin | BPGM, DHPS, FDPS | MAOA 761/4885TOP2A 1727/4885KDM4E 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.