Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 3/20 | 0.39 |
| ▸ | LDHB | P07195 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18931270 | 0.86 | ALDH1A1 (0.46) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL31684003 | 0.85 | ALDH1A1 (0.62) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL15083368 | 0.85 | ALDH1A1 (0.62) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL2500374 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL64141 | 0.78 | — | — | |
| SCHEMBL11575272 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL9772142 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL28460154 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL9727642 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL2158883 | 0.75 | ALDH1A1 (0.93) | ALDH1A1TRPA1GABRA1GABRB2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111748413-A | Coffee extract for cigarettes and preparation method and application thereof | 湖北中烟工业有限责任公司 | 2020-10-09 | — | — | CN | claimed |
| EP-0192638-A1 | LEMON-YELLOW DIAZO COMPOSITIONS | JAMES RIVER-GRAPHICS, INC. (US) | 1986-09-03 | — | — | EP | claimed |
| WO-1986001505-A1 | LEMON-YELLOW DIAZO COMPOSITIONS | JAMES RIVER GRAPHICS, INC. (US) | 1986-03-13 | — | — | WO | claimed |
| JP-57041996-A | — | — | None | — | — | JP | disclosed |
| CN-111748413-A | Coffee extract for cigarettes and preparation method and application thereof | 湖北中烟工业有限责任公司 | 2020-10-09 | — | — | CN | disclosed |
| US-6864381-B2 | Process for preparing acyloxybenzenesulfonates | CLARIANT GMBH (DE) | 2005-03-08 | — | — | US | disclosed |
| US-20040198995-A1 | Process for preparing acyloxybenzenesulfonates | CLARIANT GMBH | 2004-10-07 | — | — | US | disclosed |
| EP-1439168-A1 | Process for the preparation of acyloxybenzenesulphonates | Clariant GmbH (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-4642383-A | 2,21-DIHYDROXYDIPHENYL SULFIDES, SULFOXIDES, AND SULFONES | JAMES RIVER GRAPHICS, INC. (US) | 1987-02-10 | — | — | US | disclosed |
| EP-0192638-A1 | LEMON-YELLOW DIAZO COMPOSITIONS | JAMES RIVER-GRAPHICS, INC. (US) | 1986-09-03 | — | — | EP | disclosed |
| US-4590263-A | 3-PHENOXY-4-AMINOBENZENE DIAZONIUM SALT | JAMES RIVER GRAPHICS, INC. (US) | 1986-05-20 | — | — | US | disclosed |
| WO-1986001505-A1 | LEMON-YELLOW DIAZO COMPOSITIONS | JAMES RIVER GRAPHICS, INC. (US) | 1986-03-13 | — | — | WO | disclosed |
| JP-S5741996-A | HEAT-SENSITIVE RECORDING MEDIUM | MITSUI TOATSU CHEM INC | 1982-03-09 | — | — | JP | disclosed |
| US-4287366-A | BY OXIDATION OF THE CORRESPONDING SULFIDE OR SULFOXIDE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF AN ALKALI METAL HYDROXIDE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1981-09-01 | — | — | US | disclosed |
| US-4275240-A | OXIDATION OF 2,2'-BISPHENOL SULFIDES IN A SOLVENT | MITSUI TOATSU CHEMICALS, INC. (JP) | 1981-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198995-A1 | Process for preparing acyloxybenzenesulfonates | TST, TYR, ACMSD | ALDH1A1 943/4885TRPA1 2840/4885GABRA1 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.