Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1704721 | 0.88 | CYP1A2 (0.60) | ALDH1A1MAPK1HPGDSMN1; SMN2POLB | |
| SCHEMBL14761267 | 0.82 | CYP1A2 (0.58) | ALDH1A1MAPK1SMN1; SMN2CYP1A2CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL6282185 | 0.78 | RAB9A (0.60) | ALDH1A1SMN1; SMN2TSHRSOAT1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL1705470 | 0.77 | SOAT1 (0.52) | ALDH1A1MAPK1HPGDSMN1; SMN2POLB | |
| SCHEMBL5076188 | 0.74 | SOAT1 (0.55) | ALDH1A1MAPK1HPGDSMN1; SMN2POLB | |
| Trifluoroacetic Acid SCHEMBL7857078 | 0.74 | POLB (0.55) | ALDH1A1MAPK1HPGDSMN1; SMN2POLB | |
| SCHEMBL14761750 | 0.74 | SMN1; SMN2 (0.57) | ALDH1A1MAPK1HPGDSMN1; SMN2POLB | |
| Trifluoroacetic Acid SCHEMBL5623338 | 0.72 | ALDH1A1 (0.40) | ALDH1A1SOAT1CYP1A2NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL6280105 | 0.71 | SOAT1 (0.53) | ALDH1A1MAPK1HPGDPOLBTSHR | |
| SCHEMBL18797537 | 0.71 | SMN1; SMN2 (0.64) | ALDH1A1MAPK1HPGDSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969711-B2 | Cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| EP-0987254-B1 | NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
| EP-0987254-A1 | NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | LCAT, ACAT2, ACAT1 | ALDH1A1 307/4885MAPK1 1160/4885HPGD 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.