SCHEMBL6285316

SCHEMBL6285316

F[C]1C(F)=C(F)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CDC25B P30305 2/20 0.33
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 2/20 0.32
MAOA P21397 2/20 0.32
MAPK1 P28482 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CES2 O00748 1/20 0.32
APAF1 O14727 1/20 0.32
TERT O14746 1/20 0.32
PLIN1 O60240 1/20 0.32
TDP2 O95551 1/20 0.32
S1PR4 O95977 1/20 0.32
LMNA P02545 1/20 0.32
PLA2G1B P04054 1/20 0.32
BCHE P06276 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29231869 0.71 MEN1 (0.58) MEN1KMT2ACDC25BALDH1A1NPC1
SCHEMBL6283680 0.67 CA1 (0.41) CES2CES1
SCHEMBL10607333 0.62 MEN1 (0.65) MEN1KMT2ACDC25BALDH1A1NPC1
SCHEMBL197834 0.62 ACHE (0.47) MEN1KMT2AALDH1A1NPC1MAPK1
SCHEMBL29547174 0.62 ACHE (0.47) MEN1KMT2AALDH1A1NPC1MAPK1
SCHEMBL4368339 0.62 MEN1 (0.61) MEN1KMT2ACDC25BALDH1A1NPC1
SCHEMBL58152 0.62 MEN1 (0.61) MEN1KMT2ACDC25BALDH1A1NPC1
SCHEMBL11875421 0.62 MEN1 (0.61) MEN1KMT2ACDC25BALDH1A1NPC1
SCHEMBL49870 0.62 MEN1 (0.61) MEN1KMT2ACDC25BALDH1A1NPC1
SCHEMBL29711875 0.62 MEN1 (0.61) MEN1KMT2ACDC25BALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919291-B2 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-07-19 US disclosed
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2004-06-10 US disclosed
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization FZD7, FOS, COG4 MEN1 1928/4885KMT2A 2997/4885CDC25B 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.