Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 16/20 | 0.49 |
| ▸ | CDK1 | P06493 | 16/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 16/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 16/20 | 0.49 |
| ▸ | GSK3B | P49841 | 14/20 | 0.49 |
| ▸ | GSK3A | P49840 | 13/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 9/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282546 | 0.89 | NPY5R (0.43) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL6287306 | 0.88 | RIPK1 (0.56) | CCNB2CDK1CCNB1CCNB3NPY5R | |
| SCHEMBL6285938 | 0.86 | RIPK1 (0.47) | CCNB2CDK1CCNB1CCNB3NPY5R | |
| SCHEMBL6287083 | 0.85 | NPY5R (0.41) | NPY5RRIPK1EGFR | |
| SCHEMBL6282858 | 0.85 | NPY5R (0.41) | NPY5RRIPK1EGFR | |
| SCHEMBL6279240 | 0.83 | RIPK1 (0.43) | CCNB2CDK1CCNB1CCNB3NPY5R | |
| SCHEMBL6286923 | 0.81 | NPY5R (0.41) | CCNB2CDK1CCNB1CCNB3NPY5R | |
| SCHEMBL6285838 | 0.81 | NPY5R (0.41) | CCNB2CDK1CCNB1CCNB3NPY5R | |
| SCHEMBL6287054 | 0.81 | CLK2 (0.41) | CCNB2CDK1CCNB1CCNB3NPY5R | |
| SCHEMBL6286952 | 0.79 | NPY5R (0.39) | NPY5RRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014759-A1 | 6,5-Fused bicyclic heterocycles | PICARD JOSEPH ARMAND (US) | 2004-01-22 | — | — | US | claimed |
| EP-1294718-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-26 | — | — | EP | claimed |
| WO-2001096336-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY (US) | 2001-12-20 | — | — | WO | claimed |
| US-6943174-B2 | 6,5-Fused bicyclic heterocycles | WARNER-LAMBERT COMPANY (US) | 2005-09-13 | — | — | US | disclosed |
| US-20040014759-A1 | 6,5-Fused bicyclic heterocycles | PICARD JOSEPH ARMAND (US) | 2004-01-22 | — | — | US | disclosed |
| EP-1294718-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096336-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014759-A1 | 6,5-Fused bicyclic heterocycles | ALOX15, ALOX5, ALOX15B | CCNB2 2282/4885CDK1 1374/4885CCNB1 1280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.