SCHEMBL6286372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL241664	0.89	GSK3B (0.70)	GSK3BKMT2AMEN1POLBHDAC1
	SCHEMBL11686001	0.89	SMN1; SMN2 (0.62)	KMT2APOLBHPGDSMN1; SMN2KDM4E
	SCHEMBL16499440	0.88	GSK3B (0.57)	GSK3BKMT2AMEN1POLBHDAC1
	SCHEMBL3141694	0.83	SMN1; SMN2 (0.56)	KMT2APOLBHPGDSMN1; SMN2KDM4E
	SCHEMBL2452141	0.82	HDAC1 (0.57)	GSK3BKMT2AMEN1POLBHDAC1
	SCHEMBL100952	0.81	NR4A2 (0.65)	GSK3BKMT2AMEN1POLBHDAC1
	SCHEMBL2116189	0.81	HSD17B3 (0.67)	GSK3BKMT2AMEN1POLBHDAC1
	SCHEMBL822848	0.81	KMT2A (0.70)	GSK3BKMT2AMEN1POLBHPGD
	SCHEMBL8532385	0.81	HSD17B3 (0.67)	KMT2APOLBHPGDSMN1; SMN2KDM4E
	SCHEMBL394576	0.81	GSK3B (0.59)	GSK3BKMT2AMEN1POLBHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.