Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355454 | 0.83 | CES2 (0.53) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL7043298 | 0.82 | L3MBTL1 (0.55) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL17965782 | 0.82 | SRC (0.50) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL27970498 | 0.81 | ATM (0.44) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL6287222 | 0.81 | LMNA (0.52) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL16782694 | 0.81 | APP (0.47) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL18207061 | 0.81 | LMNA (0.52) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL8593879 | 0.81 | LMNA (0.52) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL2289610 | 0.81 | APP (0.47) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL3335866 | 0.79 | SRC (0.57) | L3MBTL1ATMKMT2AAAK1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863770-B | Cyclic amine BASE-1 inhibitors having a heterocyclic substituent | SCHERING CORP | 2011-05-25 | — | — | CN | disclosed |
| CN-1863797-A | Cyclic amine BACE-1 inhibitors having a benzamide substituent | PHARMACOPEIA DRUG DISCOVERY (US) | 2006-11-15 | — | — | CN | disclosed |
| CN-1863770-A | Cyclic amine BASE-1 inhibitors having a heterocyclic substituent | SCHERING CORP AND PHARMACOPEIA (US) | 2006-11-15 | — | — | CN | disclosed |
| US-6911468-B2 | Tyrosine phosphatase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |
| US-5505936-A | ANTI-SUNTAN OR ANTI-SUNBURN OIL BASED COSMETICS | KAO CORPORATION (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0629630-A1 | Novel phosphoric diesters which absorb UV rays, method of preparing the same, and cosmetic compositions containing the same | KAO CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-4438277-A | Hydronaphthalene derivatives | SANKYO COMPANY, LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |
| US-4361515-A | Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1982-11-30 | — | — | US | disclosed |
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | PTPRC, PTPN1, PTPRM | L3MBTL1 1502/4885ATM 1709/4885KMT2A 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.