Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287210 | 0.83 | L3MBTL1 (0.46) | CES2CES1L3MBTL1ATMKMT2A | |
| SCHEMBL27395438 | 0.82 | APP (0.41) | KMT2AAAK1CTSSCTSKALDH1A1 | |
| SCHEMBL8843604 | 0.82 | CES2 (0.60) | CES2CES1L3MBTL1ATMKMT2A | |
| SCHEMBL20166011 | 0.82 | LMNA (0.36) | CES2CES1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL26785134 | 0.82 | CES2 (0.46) | CES2CES1L3MBTL1ATMKMT2A | |
| SCHEMBL17965782 | 0.81 | SRC (0.50) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL7043298 | 0.81 | L3MBTL1 (0.55) | L3MBTL1ATMKMT2AAAK1CTSS | |
| SCHEMBL3138807 | 0.81 | MAPT (0.40) | L3MBTL1KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL8472341 | 0.81 | NPSR1 (0.47) | CES2CES1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL9462640 | 0.80 | RAB9A (0.43) | L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11819531-B2 | Multifunctional zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20230277616-A9 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC. | 2023-09-07 | — | — | US | disclosed |
| EP-2880012-B1 | COMPOUNDS | PHOTOCURE ASA (NO) | 2021-12-15 | — | — | EP | disclosed |
| EP-2880012-B1 | COMPOUNDS | PHOTOCURE ASA (NO) | 2021-12-15 | — | — | EP | disclosed |
| EP-3331890-B1 | PROTECTED ORGANOBORONIC ACIDS WITH TUNABLE REACTIVITY, AND METHODS OF USE THEREOF | UNIV ILLINOIS (US) | 2021-11-24 | — | — | EP | disclosed |
| EP-3331890-B1 | PROTECTED ORGANOBORONIC ACIDS WITH TUNABLE REACTIVITY, AND METHODS OF USE THEREOF | UNIV ILLINOIS (US) | 2021-11-24 | — | — | EP | disclosed |
| US-10844081-B2 | Protected organoboronic acids with tunable reactivity, and methods of use thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-11-24 | — | — | US | disclosed |
| US-10844081-B2 | Protected organoboronic acids with tunable reactivity, and methods of use thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-11-24 | — | — | US | disclosed |
| US-20170143841-A1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | KODIAK SCIENCES INC. | 2017-05-25 | — | — | US | disclosed |
| US-20170143841-A1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | KODIAK SCIENCES INC. | 2017-05-25 | — | — | US | disclosed |
| US-5767310-A | Phenoxyphenylacetic acid derivatives | MERCK & CO., INC. (US) | 1998-06-16 | — | — | US | disclosed |
| US-5668176-A | ENDOTHELIN ANTAGONIST | MERCK & CO. INC. (US) | 1997-09-16 | — | — | US | disclosed |
| US-5565485-A | TREATING CARDIOVASCULAR DISORDERS | MERCK & CO., INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0617001-A1 | Phenoxyphenylacetic acid derivatives | MERCK & CO. INC. (US) | 1994-09-28 | — | — | EP | disclosed |
| US-5223529-A | Nervous system and gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1993-06-29 | — | — | US | disclosed |
| US-4511720-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4355033-A | TREATMENT OF HYPERTENSION | HOFFMAN-LA ROCHE INC. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4244957-A | HYPOTENSIVE AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4144393-A | 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group | GLAXO LABORATORIES LIMITED (GB) | 1979-03-13 | — | — | US | disclosed |
| US-4103084-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (GB) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230277616-A9 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | PHOSPHO1, MSN, ZW10 | CES2 846/4885CES1 1746/4885L3MBTL1 2755/4885 |
| US-20170143841-A1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | ACP1, PHOSPHO1, PARG | CES2 1700/4885CES1 4072/4885L3MBTL1 3116/4885 |
| US-10844081-B2 | Protected organoboronic acids with tunable reactivity, and methods of use thereof | CYP2B6, HMBS, DDT | CES2 80/4885CES1 278/4885L3MBTL1 4199/4885 |
| US-11819531-B2 | Multifunctional zwitterionic polymer conjugates | PHOSPHO1, MSN, ZW10 | CES2 846/4885CES1 1746/4885L3MBTL1 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.