Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.41 |
| ▸ | PADI3 | Q9ULW8 | 2/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.41 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6290915 | 0.88 | HDAC4 (0.50) | PLGEHMT2PADI1PADI3PADI4 | |
| Trifluoroacetic Acid SCHEMBL6287789 | 0.88 | HDAC4 (0.50) | PLGEHMT2PADI1PADI3PADI4 | |
| Trifluoroacetic Acid SCHEMBL6286322 | 0.88 | MCHR1 (0.46) | PLGEHMT2PADI1PADI3PADI4 | |
| Trifluoroacetic Acid SCHEMBL6287882 | 0.84 | PYGL (0.39) | PLGEHMT2PADI1PADI3PADI4 | |
| Trifluoroacetic Acid SCHEMBL6290420 | 0.84 | FNTA (0.42) | PLGEHMT2PADI1PADI3PADI4 | |
| Trifluoroacetic Acid SCHEMBL6290412 | 0.84 | FNTA (0.42) | PLGEHMT2PADI1PADI3PADI4 | |
| Trifluoroacetic Acid SCHEMBL6286376 | 0.83 | CALCRL (0.46) | PLGEHMT2HDAC4MEF2DSSTR3 | |
| Trifluoroacetic Acid SCHEMBL6282751 | 0.83 | HPGDS (0.48) | PLGHDAC4MEF2DCA1CA12 | |
| Trifluoroacetic Acid SCHEMBL6286278 | 0.82 | CALCRL (0.47) | PLGHDAC4SSTR3CALCRLLTA4H | |
| Trifluoroacetic Acid SCHEMBL6288016 | 0.82 | CALCRL (0.47) | PLGHDAC4SSTR3CALCRLLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |