Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.39 |
| ▸ | PADI3 | Q9ULW8 | 2/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6290412 | 0.91 | FNTA (0.42) | MCHR1PLGPYGLEHMT2DEGS1 | |
| Trifluoroacetic Acid SCHEMBL6290420 | 0.91 | FNTA (0.42) | MCHR1PLGPYGLEHMT2DEGS1 | |
| Trifluoroacetic Acid SCHEMBL6287713 | 0.88 | PLG (0.43) | PLGEHMT2PADI1PADI3PADI4 | |
| Trifluoroacetic Acid SCHEMBL6287882 | 0.88 | PYGL (0.39) | PLGPYGLEHMT2PADI1PADI3 | |
| Trifluoroacetic Acid SCHEMBL6287789 | 0.86 | HDAC4 (0.50) | PLGEHMT2PADI1PADI3PADI4 | |
| Trifluoroacetic Acid SCHEMBL6290915 | 0.86 | HDAC4 (0.50) | PLGEHMT2PADI1PADI3PADI4 | |
| Trifluoroacetic Acid SCHEMBL6282751 | 0.83 | HPGDS (0.48) | PLGHDAC1HDAC4MEF2D | |
| Trifluoroacetic Acid SCHEMBL6288016 | 0.80 | CALCRL (0.47) | PLGHDAC1HDAC4 | |
| Trifluoroacetic Acid SCHEMBL6286278 | 0.80 | CALCRL (0.47) | PLGHDAC1HDAC4 | |
| Hydrochloric Acid SCHEMBL6290418 | 0.79 | DHPS (0.45) | PLGEHMT2PADI4PADI2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |