Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208629 | 0.87 | L3MBTL1 (0.35) | L3MBTL1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL7210568 | 0.87 | L3MBTL1 (0.35) | L3MBTL1TSHRMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL6290966 | 0.86 | L3MBTL1 (0.32) | L3MBTL1TSHRMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL6291011 | 0.85 | LTA4H (0.33) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| Hydrochloric Acid SCHEMBL6287860 | 0.85 | LTA4H (0.33) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| Hydrochloric Acid SCHEMBL6285978 | 0.84 | S1PR1 (0.33) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| Hydrochloric Acid SCHEMBL6287983 | 0.82 | PAOX (0.38) | S1PR1S1PR3CA1CA2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6285434 | 0.80 | PLG (0.35) | NPC1RAB9APLGKLK1KLK6 | |
| SCHEMBL6287968 | 0.79 | L3MBTL1 (0.39) | L3MBTL1MEN1KMT2ATDP1S1PR1 | |
| Trifluoroacetic Acid SCHEMBL6287794 | 0.79 | MLYCD (0.37) | MEN1KMT2ANPC1RAB9ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |