Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210568 | 1.00 | L3MBTL1 (0.35) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| SCHEMBL6287947 | 0.87 | L3MBTL1 (0.36) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| Hydrochloric Acid SCHEMBL6290966 | 0.81 | L3MBTL1 (0.32) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| SCHEMBL6287962 | 0.80 | LTA4H (0.43) | LTA4HMAPT | |
| Hydrochloric Acid SCHEMBL6287860 | 0.80 | LTA4H (0.33) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| Hydrochloric Acid SCHEMBL6291011 | 0.80 | LTA4H (0.33) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| Hydrochloric Acid SCHEMBL6285978 | 0.79 | S1PR1 (0.33) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| SCHEMBL6286636 | 0.79 | L3MBTL1 (0.43) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| SCHEMBL6287968 | 0.77 | L3MBTL1 (0.39) | L3MBTL1S1PR1S1PR3CA1CA2 | |
| SCHEMBL6283057 | 0.76 | CA1 (0.42) | CA1CA2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | MPL, THPO, TEK | L3MBTL1 1806/4885S1PR1 1281/4885S1PR3 1632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.