Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EPOR | P19235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6286778 | 0.81 | LTA4H (0.52) | LTA4HEPOR | |
| SCHEMBL7210568 | 0.80 | L3MBTL1 (0.35) | LTA4HMAPT | |
| SCHEMBL7208629 | 0.80 | L3MBTL1 (0.35) | LTA4HMAPT | |
| Hydrochloric Acid SCHEMBL31300266 | 0.80 | ALDH1A1 (0.44) | LTA4HMAOAITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL6288018 | 0.79 | CES1 (0.39) | LTA4HTP53MAPTITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL6286281 | 0.79 | CES1 (0.39) | LTA4HTP53MAPTITGB3ITGA2B | |
| SCHEMBL1167642 | 0.79 | SMN1; SMN2 (0.46) | LTA4HMAOAITGB3ITGA2B | |
| SCHEMBL1167641 | 0.79 | SMN1; SMN2 (0.46) | LTA4HMAOAITGB3ITGA2B | |
| SCHEMBL7038778 | 0.78 | KMT2A (0.47) | ITGB3 | |
| Hydrochloric Acid SCHEMBL6287860 | 0.78 | LTA4H (0.33) | LTA4HITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | MPL, THPO, TEK | LTA4H 1938/4885TP53 3089/4885MAPT 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.