SCHEMBL6288284

SCHEMBL6288284

CC(=O)O[C@]1(C(C)=O)O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.48
ALDH1A1 P00352 1/20 0.44
POLB P06746 2/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40
KMT2A Q03164 1/20 0.40
ABCB1 P08183 12/20 0.40
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
NPC1 O15118 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TSHR P16473 1/20 0.37
GAPDH P04406 1/20 0.37
SLC43A1 O75387 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29090809 0.85 MAPT (0.52) MAPTALDH1A1POLBMEN1USP2
SCHEMBL8987849 0.83 LGALS9 (0.46) MAPTPOLBABCB1SLC43A1
SCHEMBL11075412 0.83 MAPT (0.53) MAPTALDH1A1POLBMEN1USP2
SCHEMBL27514476 0.83 MAPT (0.53) MAPTALDH1A1POLBMEN1USP2
SCHEMBL7746169 0.83 MAPT (0.53) MAPTALDH1A1POLBMEN1USP2
SCHEMBL308251 0.83 MAPT (0.53) MAPTALDH1A1POLBMEN1USP2
SCHEMBL308252 0.83 MAPT (0.53) MAPTALDH1A1POLBMEN1USP2
SCHEMBL28604390 0.80 MAPT (0.57) MAPTALDH1A1POLBMEN1USP2
SCHEMBL6222324 0.80 MAPT (0.50) MAPTALDH1A1POLBMEN1USP2
SCHEMBL23898235 0.78 MAPT (0.51) MAPTALDH1A1POLBMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6900298-B2 Process for producing nucleic acid derivative MITSUBISHI CHEMICAL CORPORATION (JP) 2005-05-31 US disclosed
US-20030153745-A1 Process for producing nucleic acid derivative MITSUBISHI CHEMICAL CORPORATION (JP) 2003-08-14 US disclosed
EP-1334978-A1 Process for preparing nucleic acid derivative MITSUBISHI CHEMICAL CORPORATION (JP) 2003-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030153745-A1 Process for producing nucleic acid derivative RNGTT, POLRMT, NT5C3B MAPT 3046/4885ALDH1A1 2074/4885POLB 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.