Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.34 |
| ▸ | TUBB | P07437 | 3/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291413 | 0.93 | TUBB4A (0.38) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6291387 | 0.91 | LMNA (0.35) | LMNATP53TUBB4ATUBBTUBA3C | |
| SCHEMBL6287177 | 0.90 | TUBB4A (0.36) | LMNATP53TUBB4ATUBBTUBA3C | |
| SCHEMBL6291362 | 0.89 | TUBB4A (0.38) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6286598 | 0.84 | ALDH1A1 (0.41) | LMNATP53TUBB4ATUBBTUBA3C | |
| SCHEMBL6288553 | 0.84 | TUBB4A (0.38) | LMNATP53TUBB4ATUBBTUBA3C | |
| SCHEMBL6288651 | 0.84 | TUBB4A (0.39) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6288551 | 0.82 | PLK1 (0.40) | LMNATP53TUBB4ATUBBTUBA3C | |
| SCHEMBL6288602 | 0.81 | TUBB4A (0.38) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6288542 | 0.78 | SMN1; SMN2 (0.44) | LMNATP53TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936609-B2 | Imidazotriazines for use as phosphodiesterase inhibitors | BAYER HEALTHCARE AG (DE) | 2005-08-30 | — | — | US | disclosed |
| US-20040249148-A1 | Imidazotriazines for use as phosphodiesterase inhibitors | BAYER HEALTHCARE AG (DE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249148-A1 | Imidazotriazines for use as phosphodiesterase inhibitors | PDE3A, PDE2A, PDE4A | LMNA 2027/4885TP53 4455/4885TUBB4A 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.