Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 3/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603975 | 0.83 | ALDH1A1 (0.67) | TDP1GPR35ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL11309698 | 0.83 | ALDH1A1 (0.67) | TDP1GPR35ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL7464277 | 0.81 | ALDH1A1 (0.49) | TDP1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9701536 | 0.80 | GPR35 (0.58) | TDP1GPR35ALDH1A1SMN1; SMN2TP53 | |
| Ethane SCHEMBL28201792 | 0.79 | ALDH1A1 (0.62) | TDP1GPR35ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL34474325 | 0.79 | MAPT (0.48) | TDP1ALDH1A1SMN1; SMN2MAPK1PELI1 | |
| SCHEMBL31167616 | 0.77 | MEN1 (0.59) | TDP1GPR35ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL536487 | 0.77 | MEN1 (0.59) | TDP1GPR35ALDH1A1SMN1; SMN2TP53 | |
| Water SCHEMBL28144477 | 0.76 | MEN1 (0.58) | TDP1GPR35ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL24726553 | 0.74 | APP (0.52) | ALDH1A1MAPK1GAAKDM4EERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6840965-B2 | P-aminophenols and colorants containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-01-11 | — | — | US | disclosed |
| US-20030110577-A1 | Novel p-aminophenols and colorants containing said compounds | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | disclosed |
| EP-1222166-A2 | NOVEL P-AMINOPHENOLS AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001085683-A2 | PYRROLYL-, FURANYL- AND THIENYL-SUBSTITUTED P-AMINOPHENOLS AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030110577-A1 | Novel p-aminophenols and colorants containing said compounds | ALPP, GSTP1, GPX4 | TDP1 2983/4885GPR35 2547/4885ALDH1A1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.