Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | MDM4 | O15151 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31393787 | 1.00 | HDAC3 (0.63) | HDAC3HDAC1HDAC2MDM4TP53 | |
| SCHEMBL13186811 | 0.94 | MEN1 (0.62) | HDAC3HDAC1HDAC2MDM4TP53 | |
| SCHEMBL1110180 | 0.87 | MDM4 (0.73) | HDAC3HDAC1HDAC2MDM4TP53 | |
| SCHEMBL28195774 | 0.83 | POLB (0.64) | HDAC3HDAC1HDAC2MDM4TP53 | |
| SCHEMBL2092377 | 0.83 | GRIK1 (0.50) | HDAC3HDAC1HDAC2MDM4TP53 | |
| SCHEMBL7295433 | 0.82 | RAB9A (0.69) | HDAC3HDAC1MAPK1POLBNPC1 | |
| SCHEMBL27985042 | 0.82 | MEN1 (0.57) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19509669 | 0.81 | HDAC3 (0.66) | HDAC3HDAC1HDAC2MDM4TP53 | |
| SCHEMBL10953014 | 0.81 | HDAC3 (0.71) | HDAC3HDAC1HDAC2MDM4TP53 | |
| SCHEMBL6067716 | 0.81 | HDAC1 (0.66) | HDAC3HDAC1HDAC2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218158-A | A method of photocatalytic synthesis is at amide compound in water phase | 福建医科大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-109879833-A | 2- perfluoroalkyl benzo selenium azole compounds and preparation method thereof | 信阳农林学院 | 2019-06-14 | — | — | CN | disclosed |
| US-20140114067-A1 | BENZIMIDAZOLE DERIVATIVES AS MITOCHONDRIAL FUNCTION MODULATORS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-04-24 | — | — | US | disclosed |
| US-6888003-B2 | Method for producing 7-(pyrazole-3-yl) benzoxazoles | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | disclosed |
| US-20030050477-A1 | Method for producing 7-(pyrazole-3-yl) benzoxazoles | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-13 | — | — | US | disclosed |
| US-6160194-A | Soil decontamination using ferric chelates and peroxide | THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) | 2000-12-12 | — | — | US | disclosed |
| US-4279887-A | RADIOACTIVE SCANNING | MEDI-PHYSICS, INC. (US) | 1981-07-21 | — | — | US | disclosed |
| US-4007221-A | Manufacture of nuclear-iodinated iodine compounds of aromatic character | BASF AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140114067-A1 | BENZIMIDAZOLE DERIVATIVES AS MITOCHONDRIAL FUNCTION MODULATORS | NLN, TFAM, NDUFAB1 | HDAC3 388/4885HDAC1 285/4885HDAC2 321/4885 |
| US-20030050477-A1 | Method for producing 7-(pyrazole-3-yl) benzoxazoles | F7, F9, TPO | HDAC3 1398/4885HDAC1 1652/4885HDAC2 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.