Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 10/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | HBB | P68871 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985958 | 0.85 | MAPK1 (0.62) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL28158735 | 0.80 | MAPK1 (0.64) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL16145030 | 0.78 | MAPK1 (0.60) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL6682201 | 0.77 | MAPK1 (0.64) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL6372403 | 0.77 | ADORA2A (0.43) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL6384455 | 0.76 | P2RY2 (0.45) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL8607876 | 0.75 | MAOA (0.56) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL27593593 | 0.73 | MAPK1 (0.58) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL527297 | 0.73 | MAOA (0.49) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL591041 | 0.73 | ALDH1A1 (1.00) | MAPK1SMN1; SMN2ALDH1A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107223124-B | The compound for carrying the azomethine type of Pyrazolopyridine unit is used for the purposes of dyeing keratin fibres | 欧莱雅 | 2019-10-25 | — | — | CN | disclosed |
| CN-110035739-A | Dye composite comprising 12- hydroxy stearic acid, organic amine and dyestuff | 欧莱雅 | 2019-07-19 | — | — | CN | disclosed |
| CN-109310607-A | The compound for carrying the azomethine type of quinoline derivatives unit is used for the purposes of dyeing keratin fibres | 莱雅公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-109311879-A | Symmetrical (asymmetry) azomethine type direct dyes comprising at least one Pyrazolopyridine unit, the method for using the dyeing keratin fiber | 莱雅公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-108697624-A | The oxidising composition for including fatty material and oxygen alkylene surfactant for handling keratin material | 莱雅公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-107595671-A | The dyeing of condensation polymer comprising oxirane and expoxy propane and/or bleaching composition | 莱雅公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-107501991-A | Three aromatic azo methine direct dyess, colouring compositions, method and purposes comprising at least one unit from resorcinol | 欧莱雅 | 2017-12-22 | — | — | CN | disclosed |
| CN-107252397-A | Include fatty material and organic phospho acid composition, the method and apparatus using it | 莱雅公司 | 2017-10-17 | — | — | CN | disclosed |
| CN-107223124-A | Carrying the compound of the azomethine type of Pyrazolopyridine unit is used for the purposes of dyeing keratin fibres | 欧莱雅 | 2017-09-29 | — | — | CN | disclosed |
| CN-107049807-A | For dyeing keratinous fibres and/or the double reagent of bleaching | 欧莱雅 | 2017-08-18 | — | — | CN | disclosed |
| CN-1886115-A | Use of peptides to protect skin from hair treatment agents | WELLA AG (DE) | 2006-12-27 | — | — | CN | disclosed |
| CN-1277528-C | Dyeing compson. for kerationous fibres comprising particular dicationic diazo dye | OREAL (FR) | 2006-10-04 | — | — | CN | disclosed |
| CN-1796371-A | Dicationic bis-hydrazone compound, dye composition comprising at least one such compound, implementation process therefor and uses thereof | OREAL (FR) | 2006-07-05 | — | — | CN | disclosed |
| CN-1760192-A | Cationic diazo compounds, compositions comprising them, methods for dyeing and kit | OREAL (FR) | 2006-04-19 | — | — | CN | disclosed |
| CN-1743382-A | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | OREAL (FR) | 2006-03-08 | — | — | CN | disclosed |
| CN-1737064-A | Cationic diazo compound, compositions comprising at least one cationic diazo compound as a direct dye, a process for dyeing keratin fibers and device therefore | OREAL (FR) | 2006-02-22 | — | — | CN | disclosed |
| CN-1733757-A | Cationic diazo compounds, compositions comprising them as direct dye, process for dyeing keratin fibers and device therefor | OREAL (FR) | 2006-02-15 | — | — | CN | disclosed |
| US-6945254-B2 | Method for simultaneously dyeing and permanent shaping of hair | WELLA AKTIENGESELLSCHAFT (DE) | 2005-09-20 | — | — | US | disclosed |
| CN-1541086-A | Dyeing compson. for kerationous fibres comprising particular dicationic diazo dye | �ź㴫 | 2004-10-27 | — | — | CN | disclosed |
| US-20030084518-A1 | Method for simultaneously dyeing and permanent shaping of hair | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030084518-A1 | Method for simultaneously dyeing and permanent shaping of hair | KRT18, KMO, TYR | MAPK1 2781/4885SMN1; SMN2 4880/4885ALDH1A1 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.