Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367249 | 0.79 | ADORA2A (0.47) | ADORA2AALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL23142622 | 0.78 | KDM4E (0.42) | ALDH1A1MAPTTDP1HPGDHSD17B10 | |
| SCHEMBL6289054 | 0.77 | MAPK1 (0.57) | ADORA2AALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL526407 | 0.75 | TSHR (0.48) | ADORA2AALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL6374060 | 0.75 | ADORA2A (0.43) | ADORA2AALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL11294914 | 0.73 | ADORA2A (0.59) | ADORA2AALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL3678678 | 0.71 | TSHR (0.44) | ADORA2AALDH1A1LMNATSHRMAOA | |
| SCHEMBL27587500 | 0.70 | ADORA2A (0.55) | ADORA2AALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL11134047 | 0.70 | ADORA2A (0.46) | ADORA2AALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL28307031 | 0.70 | ALDH1A1 (0.40) | ADORA2AALDH1A1MAPK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | HUANG HSU-SHAN (TW) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | NFE2L2, NR2F2, TFAM | ADORA2A 2213/4885ALDH1A1 692/4885MAPK1 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.