Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714035 | 1.00 | SIGMAR1 (0.49) | SIGMAR1TNNC1EGFRHTR2ASOAT2 | |
| SCHEMBL455310 | 0.98 | TNNC1 (0.50) | SIGMAR1TNNC1EGFRHTR2ASOAT2 | |
| SCHEMBL363637 | 0.98 | TNNC1 (0.50) | SIGMAR1TNNC1EGFRHTR2ASOAT2 | |
| SCHEMBL29828 | 0.98 | TNNC1 (0.50) | SIGMAR1TNNC1EGFRHTR2ASOAT2 | |
| SCHEMBL7796983 | 0.98 | TNNC1 (0.50) | SIGMAR1TNNC1EGFRHTR2ASOAT2 | |
| SCHEMBL465270 | 0.98 | TNNC1 (0.50) | SIGMAR1TNNC1EGFRHTR2ASOAT2 | |
| SCHEMBL6903530 | 0.98 | TNNC1 (0.50) | SIGMAR1TNNC1EGFRHTR2ASOAT2 | |
| SCHEMBL9172117 | 0.98 | TNNC1 (0.50) | SIGMAR1TNNC1EGFRHTR2ASOAT2 | |
| SCHEMBL6905623 | 0.98 | TNNC1 (0.50) | SIGMAR1TNNC1EGFRHTR2ASOAT2 | |
| SCHEMBL2168403 | 0.98 | TNNC1 (0.50) | SIGMAR1TNNC1EGFRHTR2ASOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658718-B | Preparation method of trans-stilbene compound | 温州大学 | 2020-12-18 | — | — | CN | disclosed |
| CN-108658718-A | A kind of preparation method of trans-stilbene compounds | 温州大学 | 2018-10-16 | — | — | CN | disclosed |
| US-6900273-B1 | Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part | HITACHI CHEMICAL CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-6867323-B2 | Cross-coupling reaction of organosilicon nucleophiles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040220342-A1 | Low-hygroscopicity low-birefringence resin compositions, molding material, sheet or film obtained therefrom, and optical part | YAMASHITA YUKIHIKO (JP) | 2004-11-04 | — | — | US | disclosed |
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN | 2002-12-05 | — | — | US | disclosed |
| EP-1205517-A1 | LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001094355-A1 | CROSS-COUPLING REACTION OF ORGANOSILICON NUCLEOPHILES | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2001-12-13 | — | — | WO | disclosed |
| US-5659084-A | LEUKOTRIENE ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0279474-B1 | PROCESS FOR THE PREPARATION OF AN ESTER OF A 3-ARYL-SUBSTITUTED ACRYLIC ACID | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-09-11 | — | — | EP | disclosed |
| US-4855485-A | Process for production of cinnamates | SUN REFINING AND MARKETING COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4792623-A | CURING AGENT, EXTENDER | THE DOW CHEMICAL COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| US-4789756-A | REACTING ALKENYL AROMATIC WITH CARBON MONOXIDE AND ALCOHOL | SHELL OIL COMPANY (US) | 1988-12-06 | — | — | US | disclosed |
| EP-0279474-A1 | Process for the preparation of an ester of a 3-aryl-substituted acrylic acid | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-08-24 | — | — | EP | disclosed |
| US-4737591-A | Catalyst and process for production of cinnamates | SUN REFINING AND MARKETING COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| US-4620027-A | OXIDATIVE CARBONYLATION OF STYRENE COMPOUNDS | SUN REFINING AND MARKETING COMPANY (US) | 1986-10-28 | — | — | US | disclosed |
| US-4578507-A | Process for the production of cinnamic acid esters | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1986-03-25 | — | — | US | disclosed |
| EP-0082258-B1 | SUBSTITUTED M-PHENYLENEDIAMINES | THE DOW CHEMICAL COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| EP-0152075-A2 | Process for the production of cinnamic acid esters | MITSUBISHI KASEI CORPORATION (JP) | 1985-08-21 | — | — | EP | disclosed |
| EP-0082258-A1 | Substituted m-phenylenediamines | THE DOW CHEMICAL COMPANY (US) | 1983-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | TST, HPD, PCNA | SIGMAR1 3222/4885TNNC1 4490/4885EGFR 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.