Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6289562 | 0.80 | ALDH1A1 (0.53) | KMT2APOLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL941088 | 0.80 | KMT2A (0.54) | KMT2AL3MBTL1LMNAPOLBKDM4E | |
| SCHEMBL11108445 | 0.80 | KMT2A (0.58) | KMT2AL3MBTL1LMNAPOLBKDM4E | |
| Hydrochloric Acid SCHEMBL7312871 | 0.78 | KMT2A (0.53) | KMT2AL3MBTL1LMNAPOLBKDM4E | |
| SCHEMBL6496987 | 0.78 | KMT2A (0.53) | KMT2AL3MBTL1LMNAPOLBKDM4E | |
| SCHEMBL556208 | 0.78 | KMT2A (0.53) | KMT2AL3MBTL1LMNAPOLBKDM4E | |
| SCHEMBL338575 | 0.78 | KMT2A (0.53) | KMT2AL3MBTL1LMNAPOLBKDM4E | |
| SCHEMBL1983267 | 0.77 | L3MBTL1 (0.51) | KMT2AL3MBTL1LMNAPOLBKDM4E | |
| SCHEMBL5740022 | 0.77 | KDM4E (0.52) | KMT2AL3MBTL1LMNAPOLBKDM4E | |
| SCHEMBL7056764 | 0.75 | HPGD (0.59) | KMT2AL3MBTL1LMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900250-B2 | Polymerizable composition | TOYO INK MFG. CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20030212162-A1 | Photopolymerization using photoinitiators | TOYO INK MFG. CO., LTD. (JP) | 2003-11-13 | — | — | US | disclosed |