⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290607 | 0.81 | MAPT (0.33) | — | |
| SCHEMBL6294283 | 0.77 | FDPS (0.41) | — | |
| SCHEMBL6290581 | 0.76 | L3MBTL1 (0.31) | — | |
| SCHEMBL6290664 | 0.76 | L3MBTL1 (0.33) | — | |
| SCHEMBL6289848 | 0.73 | L3MBTL1 (0.39) | — | |
| SCHEMBL6428832 | 0.69 | KDM4E (0.34) | — | |
| SCHEMBL7086522 | 0.64 | — | — | |
| SCHEMBL27584131 | 0.64 | FDPS (0.43) | — | |
| SCHEMBL6313748 | 0.64 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL6325784 | 0.63 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872711-B2 | β-substituted β-aminoethyl phosphonate derivatives | ILEX ONCOLOGY RESEARCH S.A. (CH) | 2005-03-29 | — | — | US | claimed |
| EP-1330463-A2 | BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES | Ilex Oncology Research S.A. (CH) | 2003-07-30 | — | — | EP | claimed |
| US-20020111488-A1 | Beta-substitued beta-aminoethyl phosphonate derivatives | ILEX PRODUCTS, INC. | 2002-08-15 | — | — | US | claimed |
| WO-2002034756-A2 | BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES | ILEX ONCOLOGY RESEARCH S.A. (CH) | 2002-05-02 | — | — | WO | claimed |
| US-6872711-B2 | β-substituted β-aminoethyl phosphonate derivatives | ILEX ONCOLOGY RESEARCH S.A. (CH) | 2005-03-29 | — | — | US | disclosed |
| EP-1330463-A2 | BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES | Ilex Oncology Research S.A. (CH) | 2003-07-30 | — | — | EP | disclosed |
| US-20020111488-A1 | Beta-substitued beta-aminoethyl phosphonate derivatives | ILEX PRODUCTS, INC. | 2002-08-15 | — | — | US | disclosed |
| WO-2002034756-A2 | BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES | ILEX ONCOLOGY RESEARCH S.A. (CH) | 2002-05-02 | — | — | WO | disclosed |