SCHEMBL6289848

SCHEMBL6289848

CCOP(=O)(CC(Nc1ccc(C)nc1C)c1cc(O)c(OC)c(OC)c1)OCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
SLC5A2 P31639 1/20 0.36
LMNA P02545 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
TUBB4A P04350 3/20 0.32
TUBB P07437 3/20 0.32
TUBA3C P0DPH7 3/20 0.32
TUBA1B P68363 3/20 0.32
TUBA4A P68366 3/20 0.32
TUBB4B P68371 3/20 0.32
TUBB3 Q13509 3/20 0.32
TUBB2A Q13885 3/20 0.32
TUBB8 Q3ZCM7 3/20 0.32
TUBA3E Q6PEY2 3/20 0.32
TUBA1A Q71U36 3/20 0.32
TUBA1C Q9BQE3 3/20 0.32
TUBB6 Q9BUF5 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290664 0.91 L3MBTL1 (0.33) L3MBTL1SLC5A2CA12CA1CA2
SCHEMBL6290581 0.91 L3MBTL1 (0.31) L3MBTL1
SCHEMBL6294334 0.89 MAPT (0.38) L3MBTL1SLC5A2TUBB4ATUBBTUBA3C
SCHEMBL6291266 0.87 L3MBTL1 (0.34) L3MBTL1SLC5A2CA12CA1CA2
SCHEMBL6294330 0.80
SCHEMBL6428832 0.79 KDM4E (0.34) L3MBTL1SLC5A2LMNACA12CA1
SCHEMBL6290700 0.74 CA12 (0.36) L3MBTL1CA12CA1CA2CA9
SCHEMBL6289835 0.73
SCHEMBL6293883 0.70 LMNA (0.39) L3MBTL1LMNAMEN1KMT2APOLB
SCHEMBL6289876 0.70 KDM4E (0.46) L3MBTL1LMNAMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6872711-B2 β-substituted β-aminoethyl phosphonate derivatives ILEX ONCOLOGY RESEARCH S.A. (CH) 2005-03-29 US claimed
EP-1330463-A2 BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES Ilex Oncology Research S.A. (CH) 2003-07-30 EP claimed
US-20020111488-A1 Beta-substitued beta-aminoethyl phosphonate derivatives ILEX PRODUCTS, INC. 2002-08-15 US claimed
WO-2002034756-A2 BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES ILEX ONCOLOGY RESEARCH S.A. (CH) 2002-05-02 WO claimed
US-6872711-B2 β-substituted β-aminoethyl phosphonate derivatives ILEX ONCOLOGY RESEARCH S.A. (CH) 2005-03-29 US disclosed
EP-1330463-A2 BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES Ilex Oncology Research S.A. (CH) 2003-07-30 EP disclosed
US-20020111488-A1 Beta-substitued beta-aminoethyl phosphonate derivatives ILEX PRODUCTS, INC. 2002-08-15 US disclosed
WO-2002034756-A2 BETA-SUBSTITUTED BETA-AMINOETHYL PHOSPHONATES ILEX ONCOLOGY RESEARCH S.A. (CH) 2002-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020111488-A1 Beta-substitued beta-aminoethyl phosphonate derivatives APOB, PHOSPHO1, APOL1 L3MBTL1 666/4885SLC5A2 1961/4885LMNA 146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.