Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.30 |
| ▸ | ATF4 | P18848 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13237415 | 0.85 | P2RX7 (0.33) | EPHX2P2RX7ATF4 | |
| SCHEMBL3732990 | 0.85 | P2RX7 (0.35) | P2RX7ATF4 | |
| SCHEMBL2525179 | 0.83 | P2RX7 (0.32) | P2RX7 | |
| SCHEMBL6290175 | 0.80 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL2947754 | 0.79 | KMT2A (0.33) | EPHX2 | |
| SCHEMBL7872058 | 0.78 | P2RX7 (0.40) | EPHX2P2RX7 | |
| SCHEMBL4501235 | 0.77 | MEN1 (0.33) | P2RX7 | |
| SCHEMBL5430882 | 0.77 | GRM1 (0.34) | P2RX7 | |
| SCHEMBL13039907 | 0.77 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL20021197 | 0.76 | P2RX7 (0.33) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314254-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2012-11-20 | — | — | US | disclosed |
| US-8314254-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2012-11-20 | — | — | US | disclosed |
| US-8314254-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2012-11-20 | — | — | US | disclosed |
| EP-2233466-A1 | 4-Alkoxy-1-amino-1-cyclohexanecarboxylic acid derivatives and their use as intermediates | Bayer CropScience AG (DE) | 2010-09-29 | — | — | EP | disclosed |
| US-20100234229-A1 | Substituted Spirocyclic Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20100234229-A1 | Substituted Spirocyclic Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20100234229-A1 | Substituted Spirocyclic Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| US-7754654-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-07-13 | — | — | US | disclosed |
| US-7754654-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-07-13 | — | — | US | disclosed |
| US-20070275858-A1 | SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-11-29 | — | — | US | disclosed |
| US-20070275858-A1 | SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275858-A1 | SUBSTITUTED SPIROCYCLIC KETOENOLS | PDHX, CYP19A1, AKR1A1 | EPHX2 117/4885PKM 336/4885FKBP1A 893/4885 |
| US-20100234229-A1 | Substituted Spirocyclic Ketoenols | HSD17B7, CYP17A1, HSD17B11 | EPHX2 352/4885PKM 447/4885FKBP1A 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.