Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KCNT1 | Q5JUK3 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732991 | 0.84 | ALDH1A1 (0.32) | MEN1KMT2ABDKRB1ALDH1A1NPSR1 | |
| SCHEMBL2525180 | 0.84 | NPSR1 (0.36) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL2947754 | 0.82 | KMT2A (0.33) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL4501238 | 0.80 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1NPSR1POLB | |
| SCHEMBL728293 | 0.78 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1NPSR1ACACB | |
| SCHEMBL6290175 | 0.77 | P2RX7 (0.35) | MEN1KMT2ABDKRB1ACACBACACA | |
| SCHEMBL1153522 | 0.75 | MEN1 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2433660 | 0.75 | TSHR (0.36) | MEN1KMT2A | |
| SCHEMBL16463001 | 0.73 | OPRM1 (0.36) | MEN1KMT2AOPRM1 | |
| SCHEMBL3757635 | 0.71 | POLB (0.35) | MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861391-B1 | Trifluoromethyl-substituted spirocyclic ketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-01 | — | — | US | disclosed |