Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501235 | 0.94 | MEN1 (0.33) | P2RX7MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL12215016 | 0.91 | P2RX7 (0.33) | P2RX7MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL5430882 | 0.85 | GRM1 (0.34) | P2RX7MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL2947752 | 0.83 | EPHX2 (0.34) | P2RX7 | |
| SCHEMBL3732990 | 0.83 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL728292 | 0.83 | MEN1 (0.32) | P2RX7MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL12215020 | 0.82 | OPRM1 (0.32) | P2RX7MEN1KMT2ATUBB4ATUBB | |
| SCHEMBL6290175 | 0.82 | P2RX7 (0.35) | P2RX7MEN1KMT2APOLBOPRM1 | |
| SCHEMBL15304586 | 0.81 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL7872058 | 0.80 | P2RX7 (0.40) | P2RX7ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039014-B2 | 3′-alkoxyspirocyclopentyl-substituted tetramic and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2011-10-18 | — | — | US | disclosed |
| US-8039014-B2 | 3′-alkoxyspirocyclopentyl-substituted tetramic and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2011-10-18 | — | — | US | disclosed |
| US-8039014-B2 | 3′-alkoxyspirocyclopentyl-substituted tetramic and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2011-10-18 | — | — | US | disclosed |
| US-20100004127-A1 | 3'-ALKOXYSPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2010-01-07 | — | — | US | disclosed |
| US-20100004127-A1 | 3'-ALKOXYSPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2010-01-07 | — | — | US | disclosed |
| US-20100004127-A1 | 3'-ALKOXYSPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2010-01-07 | — | — | US | disclosed |
| WO-2007073856-A2 | 3'-ALKOXY-SPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004127-A1 | 3'-ALKOXYSPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | TPI1, PPA1, PTPRG | P2RX7 487/4885MEN1 3793/4885KMT2A 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.