SCHEMBL629041

SCHEMBL629041

CCCCc1cccc2[nH]c(Cl)nc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
TSHR P16473 2/20 0.36
GLA P06280 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
IDO1 P14902 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11398553 0.90 NPC1 (0.44) NPC1RAB9AMEN1KMT2AMGAM
SCHEMBL11014691 0.81 TSHR (0.36) NPC1RAB9ATSHRGLAKDM4E
SCHEMBL11205382 0.81 NPC1 (0.39) NPC1RAB9ATSHRKDM4EHSD17B10
SCHEMBL3857628 0.78 POLB (0.47) PTGS2KCNH2
SCHEMBL1128916 0.78 RAB9A (0.44) NPC1RAB9AKDM4ECYP1A2CYP3A4
SCHEMBL15553340 0.77 KCNH2 (0.45) PTGS2KCNH2TLR8
SCHEMBL16097301 0.77 POLB (0.46) HSD17B10PTGS2KCNH2
SCHEMBL7260713 0.77 NPC1 (0.46) NPC1RAB9ACYP1A2CNR2MGAM
SCHEMBL5551902 0.77 ALDH1A1 (0.38) TSHRGLAKDM4ECYP1A2CYP3A4
SCHEMBL6829319 0.76 CHRM1 (0.46) NPC1RAB9AKDM4ECNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102569210-A Semiconductor device packaging method and semiconductor device package NXP BV 2012-07-11 CN disclosed
EP-2453474-A1 Semiconductor device packaging method and semiconductor device package NXP B.V. (NL) 2012-05-16 EP disclosed
US-20120112351-A1 SEMICONDUCTOR DEVICE PACKAGING METHOD AND SEMICONDUCTOR DEVICE PACKAGE NXP B.V. (NL) 2012-05-10 US disclosed
EP-2421032-A1 Semiconductor Device Packaging Method and Semiconductor Device Package NXP B.V. (NL) 2012-02-22 EP disclosed