Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 16/20 | 1.00 |
| ▸ | MMP9 | P14780 | 14/20 | 1.00 |
| ▸ | MMP3 | P08254 | 11/20 | 0.74 |
| ▸ | MMP13 | P45452 | 11/20 | 0.74 |
| ▸ | MMP1 | P03956 | 10/20 | 0.74 |
| ▸ | MMP7 | P09237 | 10/20 | 0.74 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.74 |
| ▸ | MMP14 | P50281 | 1/20 | 0.71 |
| ▸ | MMP8 | P22894 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32691806 | 0.85 | MMP2 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL4653257 | 0.85 | MMP2 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL1750956 | 0.85 | MMP2 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL8283899 | 0.84 | ADAMTS4 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL1655901 | 0.84 | ADAMTS4 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7870625 | 0.84 | MMP2 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7870619 | 0.84 | MMP2 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL14540005 | 0.84 | MMP2 (1.00) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL4609253 | 0.83 | MMP2 (0.78) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL7406967 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838483-B2 | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same | SHIONOGI & CO., LTD. (JP) | 2005-01-04 | — | — | US | claimed |