Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | CDK4 | P11802 | 2/20 | 0.44 |
| ▸ | CCND1 | P24385 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411139 | 0.77 | MAOA (0.61) | MEN1KMT2AMAPTMAOAMAOB | |
| SCHEMBL7399139 | 0.75 | DDB1 (0.46) | GSK3BMEN1KMT2ACDK2MAPT | |
| SCHEMBL1355673 | 0.74 | MEN1 (0.44) | GSK3BCDK4CCND1MEN1KMT2A | |
| SCHEMBL7413975 | 0.74 | ALDH1A1 (0.59) | GSK3BCDK4CCND1CDK2CCNA2 | |
| Water SCHEMBL8678456 | 0.73 | DDB1 (0.45) | GSK3BMEN1KMT2ACDK2MAPT | |
| SCHEMBL9240983 | 0.73 | MAOA (0.47) | GSK3BMEN1KMT2APOLBMAOA | |
| SCHEMBL16226995 | 0.71 | TTR (0.51) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9246020 | 0.70 | MAOA (0.50) | GSK3BMEN1KMT2APOLBMAOA | |
| SCHEMBL7288175 | 0.70 | ELANE (0.40) | MEN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL5747221 | 0.69 | NPSR1 (0.55) | MEN1KMT2AMAPTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900194-B1 | Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors for the treatment of respiratory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-31 | — | — | US | disclosed |