Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 10/20 | 0.40 |
| ▸ | MAOB | P27338 | 10/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411139 | 0.78 | MAOA (0.61) | MEN1KMT2AMAOAMAOBTSHR | |
| SCHEMBL5747221 | 0.75 | NPSR1 (0.55) | MEN1KMT2AMAOAMAOBSMN1; SMN2 | |
| SCHEMBL6291971 | 0.74 | GSK3B (0.44) | MEN1KMT2AMAOAMAOBADORA3 | |
| SCHEMBL11344636 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL1356332 | 0.72 | TERT (0.53) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11670022 | 0.70 | MEN1 (0.48) | MEN1KMT2AMAOAMAOBTSHR | |
| SCHEMBL17726809 | 0.70 | KMT2A (0.50) | MEN1KMT2AHPGDCASP3MAPT | |
| SCHEMBL11518444 | 0.66 | MAOA (0.66) | MEN1KMT2AMAOAMAOBTSHR | |
| SCHEMBL7284252 | 0.66 | MAOA (0.63) | MEN1KMT2AMAOAMAOBTSHR | |
| SCHEMBL11638992 | 0.66 | ATG4B (0.51) | MEN1KMT2ASMN1; SMN2HPGDCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518964-B2 | Method for identifying electrophiles and nucleophiles in a sample | EICHEN YOAV (IL) | 2016-12-13 | — | — | US | disclosed |
| US-20110281742-A1 | METHOD FOR IDENTIFYING ELECTROPHILES AND NUCLEOPHILES IN A SAMPLE | EICHEN YOAV (IL) | 2011-11-17 | — | — | US | disclosed |
| US-20090305429-A1 | Method for Detecting Alkylating Agents | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-12-10 | — | — | US | disclosed |
| US-20090258430-A1 | Method for identifying electrophiles and nucleophiles in a sample | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-10-15 | — | — | US | disclosed |
| EP-2085766-A2 | Method for identifying electrophiles and nucleophiles in a sample | Technion Research and Development Foundation, Ltd. (IL) | 2009-08-05 | — | — | EP | disclosed |
| WO-2007074461-A1 | METHOD FOR DETECTING ALKYLATING AGENTS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2007-07-05 | — | — | WO | disclosed |