Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 5/20 | 0.88 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292833 | 1.00 | ATP6V1B1 (0.88) | ATP6V1B1ATP6AP1ALOX15MAPTKDM4E | |
| SCHEMBL6292838 | 1.00 | ATP6V1B1 (0.88) | ATP6V1B1ATP6AP1ALOX15MAPTKDM4E | |
| SCHEMBL8344269 | 0.87 | ATP6V1B1 (0.77) | ATP6V1B1ATP6AP1 | |
| SCHEMBL8343521 | 0.82 | ATP6V1B1 (0.80) | ATP6V1B1ATP6AP1MAPTALDH1A1PYGL | |
| SCHEMBL8351605 | 0.81 | ATP6V1B1 (0.69) | ATP6V1B1ATP6AP1ALOX15KDM4EALDH1A1 | |
| SCHEMBL6291679 | 0.79 | ATP6V1B1 (0.75) | ATP6V1B1ATP6AP1ALOX15KDM4EALDH1A1 | |
| SCHEMBL6291675 | 0.79 | ATP6V1B1 (0.75) | ATP6V1B1ATP6AP1ALOX15KDM4EALDH1A1 | |
| SCHEMBL6291678 | 0.79 | ATP6V1B1 (0.75) | ATP6V1B1ATP6AP1ALOX15KDM4EALDH1A1 | |
| SCHEMBL8343617 | 0.79 | ATP6V1B1 (0.70) | ATP6V1B1ATP6AP1KDM4EALDH1A1 | |
| SCHEMBL6292599 | 0.79 | ATP6V1B1 (0.66) | ATP6V1B1ATP6AP1ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903117-B2 | Indole derivatives for the treatment of osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2005-06-07 | — | — | US | disclosed |