Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 5/20 | 0.69 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343617 | 0.82 | ATP6V1B1 (0.70) | ATP6V1B1ATP6AP1ALDH1A1KDM4EGAA | |
| SCHEMBL8343620 | 0.82 | ATP6V1B1 (0.70) | ATP6V1B1ATP6AP1ALDH1A1KDM4EGAA | |
| SCHEMBL6292835 | 0.81 | ATP6V1B1 (0.88) | ATP6V1B1ATP6AP1ALDH1A1KDM4EALOX15 | |
| SCHEMBL6291928 | 0.79 | ATP6V1B1 (0.66) | ATP6V1B1ATP6AP1MEN1KMT2AALDH1A1 | |
| SCHEMBL8344269 | 0.79 | ATP6V1B1 (0.77) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6295636 | 0.78 | ATP6V1B1 (0.70) | ATP6V1B1ATP6AP1ALDH1A1KDM4EGAA | |
| SCHEMBL6295637 | 0.78 | ATP6V1B1 (0.70) | ATP6V1B1ATP6AP1ALDH1A1KDM4EGAA | |
| SCHEMBL6292599 | 0.76 | ATP6V1B1 (0.66) | ATP6V1B1ATP6AP1MEN1KMT2AALDH1A1 | |
| SCHEMBL6292600 | 0.76 | ATP6V1B1 (0.66) | ATP6V1B1ATP6AP1MEN1KMT2AALDH1A1 | |
| SCHEMBL6292859 | 0.76 | ATP6V1B1 (0.76) | ATP6V1B1ATP6AP1GAAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981525-A | FOR THERAPY OR PROPHYLAXIS OF OSTEOPOROSIS,TUMOURS, ULCERS, AUTOIMMUNE DISEASES, LIPIDEMIC DISORDERS, HYPERCHOLESTEROLEMIC AND ATHEROSCLEROTIC DISEASES, AIDS ALZHEIMER'S DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |