Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813777 | 0.87 | ADRB2 (0.39) | FPR2SCN9ANPSR1MEN1PLA2G1B | |
| SCHEMBL8909415 | 0.86 | KMT2A (0.40) | FPR2SCN9ANPSR1MEN1PLA2G1B | |
| SCHEMBL6299733 | 0.86 | SLC6A3 (0.35) | SLC6A3MEN1KMT2AUSP30 | |
| SCHEMBL6299731 | 0.86 | SLC6A3 (0.35) | SLC6A3MEN1KMT2AUSP30 | |
| SCHEMBL8380101 | 0.80 | KMT2A (0.45) | NPSR1MEN1PLA2G1BHTTKMT2A | |
| SCHEMBL27631962 | 0.80 | SLC6A3 (0.33) | SLC6A3FPR2SCN9ANPSR1MEN1 | |
| SCHEMBL6295154 | 0.79 | SLC6A3 (0.34) | SLC6A3MEN1KMT2AUSP30 | |
| SCHEMBL7479440 | 0.78 | MT-CO2 (0.46) | NPSR1MEN1PLA2G1BHTTKMT2A | |
| SCHEMBL7479568 | 0.78 | MT-CO2 (0.46) | NPSR1MEN1PLA2G1BHTTKMT2A | |
| SCHEMBL27824592 | 0.78 | HTT (0.35) | SLC6A3NPSR1MEN1PLA2G1BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962934-B2 | Substituted amino carboxamides for the treatment of Alzheimer's disease | ELAN PHARMACEUTICALS, INC. (US) | 2005-11-08 | — | — | US | disclosed |
| US-20030166580-A1 | Substituted amino carboxamides for the treatment of alzheimer's disease | ELAN PHARMACEUTICALS, INC. | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166580-A1 | Substituted amino carboxamides for the treatment of alzheimer's disease | BACE1, BACE2, APP | SLC6A3 3065/4885FPR2 879/4885SCN9A 2359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.