Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XPO1 | O14980 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294150 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAAXPO1CA12AKR1B10 | |
| SCHEMBL5369758 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GAACA12CA1CA2 | |
| SCHEMBL5381056 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAAXPO1CA12CA1 | |
| SCHEMBL5381060 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAAXPO1CA12CA1 | |
| SCHEMBL5372979 | 0.70 | POLB (0.35) | ALDH1A1GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5373017 | 0.70 | ALDH1A1 (0.34) | ALDH1A1GAASMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL764718 | 0.70 | ALDH1A1 (0.36) | ALDH1A1GAASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL6294806 | 0.67 | POLB (0.33) | ALDH1A1GAAL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL6848494 | 0.67 | CYP1A2 (0.37) | ALDH1A1GAASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL4625429 | 0.64 | PLAT (0.43) | ALDH1A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142820-A1 | Pyrazolylarylalkines | VENTURE LENDING & LEASING IX, INC. | 2004-07-22 | — | — | US | claimed |
| US-6916839-B2 | Pyrazolylarylalkines | BAYER CHEMICALS AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040142820-A1 | Pyrazolylarylalkines | VENTURE LENDING & LEASING IX, INC. | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142820-A1 | Pyrazolylarylalkines | CBR3, PPOX, ALK | ALDH1A1 603/4885GAA 2512/4885XPO1 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.