SCHEMBL6294238

SCHEMBL6294238

CN1C(=O)C(Sc2ccccc2)C(=O)N(C)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.38
ALDH1A1 P00352 8/20 0.38
HSD17B10 Q99714 4/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 6/20 0.38
MEN1 O00255 4/20 0.38
KDM4C Q9H3R0 3/20 0.38
POLB P06746 3/20 0.37
TSHR P16473 2/20 0.37
MAPK1 P28482 1/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
DDB1 Q16531 1/20 0.34
CRBN Q96SW2 1/20 0.34
KDM4A O75164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CARM1 Q86X55 1/20 0.34
PRMT6 Q96LA8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9838569 0.73 SRC (0.41) ALDH1A1TSHR
SCHEMBL64294 0.69 KMT2A (0.48) MAPTALDH1A1HSD17B10GAAKMT2A
SCHEMBL10338581 0.69 KMT2A (0.41) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL4663179 0.66 LOX (0.59) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL4435666 0.65 KMT2A (0.72) MAPTALDH1A1HSD17B10GAAKMT2A
SCHEMBL6837118 0.64 EP300 (0.57) MAPTALDH1A1HSD17B10GAAKMT2A
SCHEMBL472476 0.64 KDM4C (0.51) MAPTALDH1A1HSD17B10KMT2AMEN1
SCHEMBL6218393 0.63 DDB1 (0.43) MAPTALDH1A1HSD17B10KMT2AKDM4E
SCHEMBL1461678 0.63 TSHR (0.46) KMT2AMEN1TSHRKDM4E
SCHEMBL1334635 0.63 MAPT (0.46) MAPTALDH1A1HSD17B10KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6953535-B2 Initiator system for acid dental formulations 3M ESPE AG (DE) 2005-10-11 US disclosed
US-20040097613-A1 Initiator system for acid dental formulations 3M INNOVATIVE PROPERTIES COMPANY 2004-05-20 US disclosed