SCHEMBL64294

SCHEMBL64294

CN1C(=O)C(c2ccccc2)C(=O)N(C)C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
TSHR P16473 3/20 0.48
MAPT P10636 4/20 0.45
MAPK1 P28482 2/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
HTR2B P41595 1/20 0.45
ALDH1A1 P00352 2/20 0.44
GFER P55789 1/20 0.44
CHEK1 O14757 1/20 0.42
AURKA O14965 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
PAK4 O96013 1/20 0.42
ABL1 P00519 1/20 0.42
NTRK1 P04629 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294237 0.83 KMT2A (0.46) KMT2ATSHRMAPTMAPK1LMNA
SCHEMBL21292115 0.82 TSHR (0.40) KMT2ATSHRMAPTMAPK1LMNA
SCHEMBL17717960 0.78 EP300 (0.44) KMT2ATSHRMAPTMAPK1CYP3A4
SCHEMBL26133735 0.77 DPP4 (0.41) KMT2AMAPTLMNACYP1A2ALDH1A1
SCHEMBL15460833 0.76 ALDH1A1 (0.44) KMT2ATSHRMAPTMAPK1LMNA
SCHEMBL29915854 0.76 CHEK1 (0.49) KMT2ATSHRMAPTMAPK1LMNA
SCHEMBL9952138 0.76 CHEK1 (0.49) KMT2ATSHRMAPTMAPK1LMNA
SCHEMBL1461678 0.75 TSHR (0.46) KMT2ATSHRLMNAKDM4EMEN1
SCHEMBL17070930 0.74 HPGD (0.57) KMT2ATSHRMAPTMAPK1LMNA
SCHEMBL1639999 0.72 ALDH1A1 (0.47) KMT2AMAPTMAPK1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US claimed
EP-4508111-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME Huntsman Petrochemical LLC (US) 2025-02-19 EP claimed
WO-2023200641-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC (US) 2023-10-19 WO claimed
US-9668943-B2 Dental conditioning composition KABUSHIKI KAISHA SHOFU (JP) 2017-06-06 US claimed
US-7488762-B2 Two paste-type glass ionomer cement KABUSHIKI KAISHA SHOFU (JP) 2009-02-10 US claimed
EP-1387659-B1 INITIATOR SYSTEM FOR ACID DENTAL FORMULATIONS 3M ESPE AG (DE) 2008-05-07 EP claimed
US-6784224-B2 STORAGE STABLE, GELATION INHIBITION, CONSISTS OF (METH)ACRYLATE MONOMERS, A FILLER AND A PYRIMIDINETRIONES CATALYST; MULTI-PASTES CONTAINS DIFFERENT COMPONENTS, MIXED WITH EACH OTHER TO POLYMERIZE; DENTAL ADHESIVES GC CORPORATION (JP) 2004-08-31 US claimed
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH SHOFU INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4717251-A2 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2026-03-12 US disclosed
EP-3733152-B1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC (JP) 2026-03-11 EP disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
WO-1999043288-A1 IMPROVED CATALYTIC POLYMERIZATION ACCELERATOR SYSTEMS MYCONE DENTAL SUPPLY COMPANY, INC. (US) 1999-09-02 WO disclosed
US-5883153-A SUSTAINED RELEASE GLASS IONOMERS SHOFU INC. (JP) 1999-03-16 US disclosed
US-5707611-A Tooth surface treating agent KABUSHIKI KAISHA SHOFU (JP) 1998-01-13 US disclosed
EP-0702948-A1 TOOTH SURFACE TREATMENT KABUSHIKI KAISHA SHOFU (JP) 1996-03-27 EP disclosed
EP-0694298-A1 PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME SHOFU INC. (JP) 1996-01-31 EP disclosed
US-5264513-A Dental adhesive KABUSHIKI KAISHA SHOFU (JP) 1993-11-23 US disclosed
US-4873269-A MICROWAVE CURABLE METHACRYLATE ESTER POLYMER POWDER, LIQUID MONOMER, CROSSLINKING AGENT G-C DENTAL INDUSTRIAL CORP. (JP) 1989-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION GRIN3A, HBG1, ASIC1 KMT2A 2629/4885TSHR 3161/4885MAPT 2952/4885
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 KMT2A 939/4885TSHR 3276/4885MAPT 2976/4885
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH CAD, SMCHD1, ITGA1 KMT2A 1586/4885TSHR 3502/4885MAPT 991/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL KMT2A 2306/4885TSHR 4185/4885MAPT 4304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.