Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613584 | 0.84 | HTR2A (0.31) | HTR2A | |
| Hydrochloric Acid SCHEMBL8169416 | 0.77 | HTR2A (0.38) | HTR2A | |
| Hydrochloric Acid SCHEMBL6558643 | 0.77 | DRD2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6557770 | 0.74 | ADRA2C (0.34) | — | |
| Hydrochloric Acid SCHEMBL8577803 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL6557423 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6558674 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6559813 | 0.72 | IDO1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL9065089 | 0.71 | — | — | |
| SCHEMBL28088891 | 0.71 | HTR1A (0.32) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852660-B2 | Solid metallocene catalyst system | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2005-02-08 | — | — | US | claimed |
| US-20030144436-A1 | Coorination catalyst for polyalpha-olefins | MITCHELL KENT E (US) | 2003-07-31 | — | — | US | claimed |
| WO-1999043724-A1 | METHOD FOR POLYMERIZING MONOMERS TO PRODUCE LINEAR, LOW DENSITY POLYMER | PHILLIPS PETROLEUM COMPANY (US) | 1999-09-02 | — | — | WO | claimed |
| EP-0685495-B1 | Method for using a supported metallocene catalyst system | PHILLIPS PETROLEUM CO (US) | 1998-04-08 | — | — | EP | claimed |
| EP-0685495-A1 | Method for making and using a supported metallocene catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 1995-12-06 | — | — | EP | claimed |