SCHEMBL629607

SCHEMBL629607

COc1c(CO[C]=O)cc(C)c(C)c1OC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1810455 0.78
SCHEMBL9061527 0.78 KMT2A (0.34) IMPDH2
SCHEMBL7744202 0.75 ACHE (0.38) IMPDH2
SCHEMBL6995298 0.71 CYP1A2 (0.54)
SCHEMBL2027829 0.70 AOC3 (0.46)
SCHEMBL7003956 0.67 CYP3A4 (0.48)
SCHEMBL10766986 0.67 ALDH1A1 (0.30)
SCHEMBL5454389 0.66 ACHE (0.40) IMPDH2
SCHEMBL1826769 0.66 PYCR1 (0.41)
SCHEMBL2094571 0.66 TAAR1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107002293-B Sequencing by synthesis using pulsed readout optics 艾比斯生物科学公司 2020-12-08 CN claimed
US-20200123605-A1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS IBIS BIOSCIENCES, INC. 2020-04-23 US claimed
EP-3194643-B1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS IBIS BIOSCIENCES INC (US) 2020-02-19 EP claimed
US-10550428-B2 Sequencing by synthesis using pulse read optics IBIS BIOSCIENCES, INC. (US) 2020-02-04 US claimed
US-20170247755-A1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS IBIS BIOSCIENCES, INC. 2017-08-31 US claimed
EP-3194643-A1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS Ibis Biosciences, Inc. (US) 2017-07-26 EP claimed
WO-2016044391-A1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS IBIS BIOSCIENCES, INC. (US) 2016-03-24 WO claimed
US-8975216-B2 Articles having localized molecules disposed thereon and methods of producing same PACIFIC BIOSCIENCES OF CALIFORNIA (US) 2015-03-10 US claimed
EP-1958955-B1 Spatially addressable oligonucleotide arrays and method of making the same CORNELL RES FOUNDATION INC (US) 2013-09-04 EP claimed
US-7879579-B2 Detection of preferential nucleotide sequences on solid support; generate solid support, incubate with nucleotide sequences, expose to probe, detect signal, presence of signal indicates preferential nucleotide sequences CORNELL RESEARCH FOUNDATION, INC. (US) 2011-02-01 US claimed
US-20030022182-A1 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays CORNELL RESEARCH FOUNDATION, INC. 2003-01-30 US claimed
JP-2001519648-A 2001-10-23 JP claimed
EP-1143916-A2 TOPICAL COMPOSITIONS COMPRISING PROTECTED FUNCTIONAL THIOLS THE PROCTER & GAMBLE COMPANY (US) 2001-10-17 EP claimed
WO-2000040210-A2 TOPICAL COMPOSITIONS COMPRISING PROTECTED FUNCTIONAL THIOLS THE PROCTER & GAMBLE COMPANY (US) 2000-07-13 WO claimed
EP-0920440-A2 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RESEARCH FOUNDATION, INC. (US) 1999-06-09 EP claimed
WO-1997031256-A2 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RESEARCH FOUNDATION, INC. (US) 1997-08-28 WO claimed
EP-0733213-A1 PROCESS FOR THE PRODUCTION OF COMBINATORIAL COMPOUND LIBRARIES Novartis AG (CH) 1996-09-25 EP claimed
WO-1995016209-A1 PROCESS FOR THE PRODUCTION OF COMBINATORIAL COMPOUND LIBRARIES CIBA-GEIGY AG (CH) 1995-06-15 WO claimed
US-5412087-A Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces AFFYMAX TECHNOLOGIES N.V. (AN) 1995-05-02 US claimed
WO-1993022680-A1 SPATIALLY-ADDRESSABLE IMMOBILIZATION OF OLIGONUCLEOTIDES AND OTHER BIOLOGICAL POLYMERS ON SURFACES AFFYMAX TECHNOLOGIES N.V. (AN) 1993-11-11 WO claimed