Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 3/20 | 0.34 |
| ▸ | CA6 | P23280 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003956 | 0.77 | CYP3A4 (0.48) | CYP3A4MAPTHTR2ALMNAMAPK1 | |
| SCHEMBL1884279 | 0.77 | ACHE (0.45) | ACHEIMPDH2CYP3A4MAPTPTGS2 | |
| SCHEMBL6995298 | 0.77 | CYP1A2 (0.54) | CYP3A4MAPTPTGS2MAPK1SMN1; SMN2 | |
| SCHEMBL8394 | 0.75 | PTGS2 (0.53) | ACHECYP3A4MAPTPTGS2CA1 | |
| SCHEMBL629607 | 0.75 | IMPDH2 (0.31) | IMPDH2 | |
| SCHEMBL1810455 | 0.73 | — | — | |
| SCHEMBL2027829 | 0.72 | AOC3 (0.46) | MAPTLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1807876 | 0.71 | ABCB1 (0.50) | CYP3A4CA1CA2LMNAMAPK1 | |
| SCHEMBL27871754 | 0.70 | CYP3A4 (0.35) | CYP3A4HTR2AALDH1A1HPGD | |
| SCHEMBL684130 | 0.69 | ACHE (0.59) | ACHECYP3A4MAPTPTGS2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416714-B1 | USED IN AS SUPPORTS IN SOLID PHASE CHEMICAL AND BIOCHEMICAL SYNTHESES, IMMUNOASSAYS AND HYBRIDIZATION REACTIONS; APPLICATION OF DATA STORAGE TECHNOLOGY TO MOLECULAR TRACKING AND IDENTIFICATION | DISCOVERY PARTNERS INTERNATIONAL, INC. | 2002-07-09 | — | — | US | disclosed |
| US-6331273-B1 | APPLICATION OF DATA STORAGE TECHNOLOGY TO MOLECULAR TRACKING AND IDENTIFICATION; MOLECULES AND BIOLOGICAL PARTICLES CAN BE IDENTIFIED BY RETRIEVING THE STORED DATA POINTS; | DISCOVERY PARTNERS INTERNATIONAL | 2001-12-18 | — | — | US | disclosed |
| US-6306975-B1 | Radiation-grafted solid supports for chemical synthesis | IRORI | 2001-10-23 | — | — | US | disclosed |
| EP-0959985-A2 | METHODS FOR RADIATION GRAFTING TO POLYMERIC SURFACES | Irori (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998031732-A2 | METHODS FOR RADIATION GRAFTING TO POLYMERIC SURFACES | IRORI (US) | 1998-07-23 | — | — | WO | disclosed |
| US-5627283-A | ANTITHROMBIN COMPOUNDS | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0513543-B1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE AG (DE) | 1995-10-25 | — | — | EP | disclosed |
| US-5457114-A | Antithrombin; antithrombotic, enzyme resistance, tolerability | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| EP-0513543-A1 | Derivatives of amidinophenylalanine, procedure for their preparation, their utilisation and anticoagulant compositions comprising them. | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-11-19 | — | — | EP | disclosed |