Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564377 | 1.00 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8497623 | 0.93 | CA1 (0.56) | CA12CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL8498491 | 0.91 | CA1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11316968 | 0.87 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10350437 | 0.86 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11409076 | 0.86 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3136387 | 0.82 | HTT (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6588098 | 0.81 | KDM4E (0.36) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL11061442 | 0.80 | KCNH2 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1856965 | 0.79 | ERN1 (0.48) | CA1CA2CA7CA9CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6955921-B2 | Trypsin substrate and diagnostic device, and method of using same | BAYER CORPORATION (US) | 2005-10-18 | — | — | US | disclosed |
| US-6770764-B2 | DIAGNOSIS OF BACTERIA INFECTIONS | BAYER CORPORATION | 2004-08-03 | — | — | US | disclosed |
| US-20030125577-A1 | Trypsin substrate and diagnostic device, and method of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2003-07-03 | — | — | US | disclosed |
| EP-0877237-B1 | Foil for UV dosimeter | SYNTEC GES FUER CHEMIE UND TEC (DE) | 2002-12-04 | — | — | EP | disclosed |
| US-20020004219-A1 | Trypsin substrate and diganostic device, and method of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2002-01-10 | — | — | US | disclosed |
| EP-1157984-A2 | Trypsin substrate and diagnostic device, and method of using same | Bayer Corporation (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-0877237-A2 | Foil for UV dosimeter | Syntec Gesellschaft für Chemie und Technologie der Informationsaufzeichnung mbH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5736408-A | COLORIMETRIC PHOTOMETRIC QUANTITATIVE ANALYSIS | CHIMERA RESEARCH AND CHEMICAL INC. | 1998-04-07 | — | — | US | disclosed |
| EP-0158225-B1 | ANALYSIS METHOD AND MEANS FOR DETECTING ESTEROLYTIC AND/OR PROTEOLYTIC ENZYMES | MILES INC. (US) | 1992-03-11 | — | — | EP | disclosed |
| EP-0157360-B1 | CHROMOGENIC ESTERS OF AMINO ACIDS AND PEPTIDES, PROCESSES FOR THEIR PREPARATION, USE OF THESE AGENTS IN METHODS OF ANALYSIS AND AGENTS FOR DETECTION OF ESTEROLYTIC AND/OR PROTEOLYTIC ENZYMES | MILES INC. (US) | 1991-08-14 | — | — | EP | disclosed |
| EP-0039880-B2 | AGENTS FOR THE DETECTION OF ESTEROLYTIC AND/OR PROTEOLYTIC ENZYMES; AND PHENOXY-AMINO ACIDS AND PHENOXY-PEPTIDE ESTERS SUITABLE AS SUBSTRATES THEREFOR, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN PRODUCING THE AGENTS | Roche Diagnostics GmbH (DE) | 1987-06-03 | — | — | EP | disclosed |
| US-4551428-A | COLORIMETRIC ANALYSIS USING DIAZONIUM COUPLERS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-11-05 | — | — | US | disclosed |
| EP-0158225-A2 | Analysis method and means for detecting esterolytic and/or proteolytic enzymes | MILES INC. (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0157361-A2 | Analysis method and means for detecting esterolytic and or proteolytic enzymes | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |
| EP-0157360-A2 | Chromogenic esters of amino acids and peptides, processes for their preparation, use of these agents in methods of analysis and agents for detection of esterolytic and/or proteolytic enzymes | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |
| EP-0120396-A2 | Test strip for the detection of leucocytes in urine | MACHEREY-NAGEL & Co, Chemikalienhandel (DE) | 1984-10-03 | — | — | EP | disclosed |
| EP-0039880-B1 | AGENTS FOR THE DETECTION OF ESTEROLYTIC AND/OR PROTEOLYTIC ENZYMES; AND PHENOXY-AMINO ACIDS AND PHENOXY-PEPTIDE ESTERS SUITABLE AS SUBSTRATES THEREFOR, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN PRODUCING THE AGENTS | Roche Diagnostics GmbH (DE) | 1983-06-29 | — | — | EP | disclosed |
| EP-0039880-A1 | Agents for the detection of esterolytic and/or proteolytic enzymes; and phenoxy-amino acids and phenoxy-peptide esters suitable as substrates therefor, process for their production and their use in producing the agents | Roche Diagnostics GmbH (DE) | 1981-11-18 | — | — | EP | disclosed |
| US-4289839-A | BLOCKED COUPLER LIBERATED BY PHOTOCHEMICALLY FORMED ACID | JAMES RIVER GRAPHICS, INC. (US) | 1981-09-15 | — | — | US | disclosed |
| US-4252884-A | DIAZONIUM SALT, BLOCKED PHENOLIC COUPLER | JAMES RIVER GRAPHICS, INC. (US) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004219-A1 | Trypsin substrate and diganostic device, and method of using same | PRSS3, CTRL, PRSS2 | CA12 763/4885CA1 239/4885CA2 1267/4885 |
| US-20030125577-A1 | Trypsin substrate and diagnostic device, and method of using same | CTRL, PRSS3, SPINT2 | CA12 1014/4885CA1 444/4885CA2 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.