Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709413 | 0.93 | GAA (0.41) | HTTGAACA1CA2CA7 | |
| SCHEMBL6297073 | 0.82 | CA12 (0.48) | HTTGAACA1CA2CA7 | |
| SCHEMBL10564377 | 0.82 | CA12 (0.48) | HTTGAACA1CA2CA7 | |
| SCHEMBL28686179 | 0.79 | VEGFA (0.37) | — | |
| SCHEMBL11409076 | 0.79 | CA12 (0.48) | HTTCA1CA2CA7CA9 | |
| SCHEMBL6851412 | 0.78 | AR (0.40) | GAAMAPTACHEKDM4EALDH1A1 | |
| SCHEMBL1964108 | 0.77 | CA1 (0.34) | CA1CA2CA7CA9CA12 | |
| SCHEMBL28034889 | 0.77 | TDP1 (0.37) | CYP1A2CYP2A6ALDH1A1SMN1; SMN2 | |
| SCHEMBL29094042 | 0.76 | ACHE (0.31) | ACHE | |
| SCHEMBL6587771 | 0.74 | ALDH1A1 (0.31) | CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028933-B | Novel method for preparing phosphoryl azo compounds | 湖南理工学院 | 2022-08-19 | — | — | CN | claimed |
| CN-112028933-A | Novel method for preparing phosphoryl azo compounds | 湖南理工学院 | 2020-12-04 | — | — | CN | claimed |
| CN-108069868-B | Method for preparing organic amide compound from aryl diazo tetrafluoroborate and nitrile | 湖南理工学院 | 2020-11-13 | — | — | CN | claimed |
| CN-107935882-B | Method for preparing trans-aromatic tertiary amine azo compound with high stereoselectivity | 湖南理工学院 | 2020-11-13 | — | — | CN | claimed |
| CN-108069868-A | A kind of method that organic amide class compound is prepared with aryldiazonium tetrafluoroborate and nitrile | 湖南理工学院 | 2018-05-25 | — | — | CN | claimed |
| CN-112028933-B | Novel method for preparing phosphoryl azo compounds | 湖南理工学院 | 2022-08-19 | — | — | CN | disclosed |
| CN-112028933-A | Novel method for preparing phosphoryl azo compounds | 湖南理工学院 | 2020-12-04 | — | — | CN | disclosed |
| CN-108069868-B | Method for preparing organic amide compound from aryl diazo tetrafluoroborate and nitrile | 湖南理工学院 | 2020-11-13 | — | — | CN | disclosed |
| CN-107935882-B | Method for preparing trans-aromatic tertiary amine azo compound with high stereoselectivity | 湖南理工学院 | 2020-11-13 | — | — | CN | disclosed |
| CN-107382886-B | Method for constructing N-2-aryl substituted-1, 2, 3-triazole | 华南理工大学 | 2020-06-19 | — | — | CN | disclosed |
| CN-108069868-A | A kind of method that organic amide class compound is prepared with aryldiazonium tetrafluoroborate and nitrile | 湖南理工学院 | 2018-05-25 | — | — | CN | disclosed |
| CN-107935882-A | A kind of method that highly-solid selectively prepares trans fragrant tertiary amine azo compound | 湖南理工学院 | 2018-04-20 | — | — | CN | disclosed |
| CN-107382886-A | A kind of structure N 2 aryl substitutes the method for 1,2,3 triazoles | 华南理工大学 | 2017-11-24 | — | — | CN | disclosed |
| US-20100004271-A1 | HETEROCYCLIC COMPOUNDS AS AGANIST FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2010-01-07 | — | — | US | disclosed |
| EP-1899309-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003419-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004271-A1 | HETEROCYCLIC COMPOUNDS AS AGANIST FOR THE THYROID RECEPTOR | TSHR, GHSR, TRHR | HTT 307/4885GAA 1547/4885CA1 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.