Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12693538 | 0.90 | KDM4E (0.66) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL7997079 | 0.89 | KDM4E (0.54) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL27202970 | 0.84 | MAPT (0.55) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL28797567 | 0.84 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL12419937 | 0.83 | PPARG (0.50) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL5455910 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL15862062 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL30211954 | 0.83 | LOXL2 (0.51) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL13553385 | 0.82 | PPARG (0.51) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL6179410 | 0.81 | GAA (0.58) | KDM4EALDH1A1MAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415553-B | Plasticized thermoset resins and related cured resins, curing methods, and articles comprising cured resins | 马萨诸塞大学 | 2022-08-05 | — | — | CN | claimed |
| EP-3481899-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | The University of Massachusetts (US) | 2019-05-15 | — | — | EP | claimed |
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | claimed |
| WO-2018008003-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | THE UNIVERSITY OF MASSACHUSETTS (US) | 2018-01-11 | — | — | WO | claimed |
| EP-3481899-B1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | UNIV MASSACHUSETTS (US) | 2022-12-21 | — | — | EP | disclosed |
| CN-109415553-B | Plasticized thermoset resins and related cured resins, curing methods, and articles comprising cured resins | 马萨诸塞大学 | 2022-08-05 | — | — | CN | disclosed |
| US-10913844-B2 | Plasticized thermoset resin, and associated cured resin, method of curing, and article comprising cured resin | THE UNIVERSITY OF MASSACHUSETTS (US) | 2021-02-09 | — | — | US | disclosed |
| US-20190309159-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | THE UNIVERSITY OF MASSACHUSETTS | 2019-10-10 | — | — | US | disclosed |
| EP-3481899-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | The University of Massachusetts (US) | 2019-05-15 | — | — | EP | disclosed |
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | disclosed |
| WO-2018008003-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | THE UNIVERSITY OF MASSACHUSETTS (US) | 2018-01-11 | — | — | WO | disclosed |
| US-6911469-B2 | Sulfonamide compounds and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20040180947-A1 | hypoglycemic activity or phoshodiesterase-V inhibitory activity; prophylaxis and treatment of impaired glucose tolerance disorder, diabetes (e.g., type II diabetes), diabetic complications | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| US-20020099212-A1 | For therapy of disease treatable based on a blood sugar level-depressing activity or a disease treatable based on a cGMP-PDE inhibiting activity, smooth muscle relaxing activity, bronchodilating activity, vasodilating activity | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-07-25 | — | — | US | disclosed |
| US-6348474-B1 | COMPOUNDS AS ANTIDIABETIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-0995742-A1 | SULFONAMIDE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0061907-A1 | Secondary amines, their preparation, pharmaceutical compositions containing them and their use | BEECHAM GROUP PLC (GB) | 1982-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099212-A1 | For therapy of disease treatable based on a blood sugar level-depressing activity or a disease treatable based on a cGMP-PDE inhibiting activity, smooth muscle relaxing activity, bronchodilating activity, vasodilating activity | PDE2A, PDE3A, PDE12 | KDM4E 1305/4885ALDH1A1 570/4885MAPT 4591/4885 |
| US-20040180947-A1 | hypoglycemic activity or phoshodiesterase-V inhibitory activity; prophylaxis and treatment of impaired glucose tolerance disorder, diabetes (e.g., type II diabetes), diabetic complications | PDE2A, PDE3A, PYGM | KDM4E 935/4885ALDH1A1 1067/4885MAPT 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.