Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516473 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAOAKDM4EGLAL3MBTL1 | |
| SCHEMBL10090559 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAOAKDM4EGLAL3MBTL1 | |
| SCHEMBL6301209 | 0.81 | KMT2A (0.36) | ALDH1A1MAOAKDM4EGLAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2960051 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAOAKDM4EGLAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2960053 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAOAKDM4EGLAL3MBTL1 | |
| SCHEMBL3803101 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAOAKDM4EGLAL3MBTL1 | |
| SCHEMBL10122037 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAOAKDM4EGLAL3MBTL1 | |
| SCHEMBL3803095 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MAOAKDM4EGLAL3MBTL1 | |
| SCHEMBL6305009 | 0.78 | KMT2A (0.34) | ALDH1A1MAOAKDM4EGLAL3MBTL1 | |
| SCHEMBL6301891 | 0.76 | KMT2A (0.33) | ALDH1A1MAOAKDM4EGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759677-A | Solid catalyst component for olefin polymerization, catalyst and application thereof | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112759676-A | Solid catalyst component for preparing polyolefin, catalyst and application thereof | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112759528-A | Novel imidate compound and preparation method thereof | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112759672-A | Solid catalyst component for olefin polymerization, catalyst and application thereof | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-108699217-A | Epoxy resin composition, semi-cured epoxy resin composition, molded article, and molded cured article | 日立化成株式会社 | 2018-10-23 | — | — | CN | disclosed |
| US-6911469-B2 | Sulfonamide compounds and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-6890934-B2 | Sulfonamide compounds and uses thereof as medicines | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-10 | — | — | US | disclosed |
| US-20040180947-A1 | hypoglycemic activity or phoshodiesterase-V inhibitory activity; prophylaxis and treatment of impaired glucose tolerance disorder, diabetes (e.g., type II diabetes), diabetic complications | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| US-20030171396-A1 | Sulfonamide compounds and uses thereof as medicines | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| US-6573274-B1 | Treatment of the diseases curable based on a hypoglycemic action, and the diseases curable based on a cGMP-PDE inhibitory action, a smooth muscle relaxing action, a bronchodilating action, a vasodilating action, a smooth muscle | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| US-5322842-A | Tricyclic benzodiazepine derivates, their preparation, and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0360079-B1 | Tricyclic compounds, processes for their preparation and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-5248679-A | Tricyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-28 | — | — | US | disclosed |
| CN-1022187-C | Method for preparation of tricyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-09-22 | — | — | CN | disclosed |
| EP-0544909-A1 | TRICYCLIC BENZODIAZEPINE DERIVATES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-5155101-A | Tricyclic compounds | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| WO-1992003438-A1 | TRICYCLIC BENZODIAZEPINE DERIVATES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-05 | — | — | WO | disclosed |
| US-4981847-A | Tricyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
| CN-1040981-A | Tricyclic compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1990-04-04 | — | — | CN | disclosed |
| EP-0360079-A1 | Tricyclic compounds, processes for their preparation and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171396-A1 | Sulfonamide compounds and uses thereof as medicines | PDE2A, PDE3A, PDE5A | ALDH1A1 476/4885MAOA 2022/4885KDM4E 1599/4885 |
| US-20040180947-A1 | hypoglycemic activity or phoshodiesterase-V inhibitory activity; prophylaxis and treatment of impaired glucose tolerance disorder, diabetes (e.g., type II diabetes), diabetic complications | PDE2A, PDE3A, PYGM | ALDH1A1 1067/4885MAOA 489/4885KDM4E 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.